
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN: 9780134580999
Author: Elaine N. Marieb, Katja N. Hoehn
Publisher: PEARSON
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Transcribed Image Text:2.
356
Q7. Haemophiliacs possess a non-functional form of the gene responsible for the production of
blood clotting factors. Shown below is the occurrence of haemophilia in one family.
Completed forms to be made available for external moderation.
4.
= male
= female
= male haemophiliac
8.
1.
5.
6
3.
4.
11
12
Using the following symbols:
H= dominant allele h = recessive allele
1) State the genotypes of the following individuals.
Individual
Genotype
1.
HH
ЧАН
HH
9.
6.
2) On the basis of the information provided, is the inheritance of haemophilia:
1) autosomal or sex-linked? Sex-linked
(ii) dominant or recessive? Recessive
3) State the probability of individual 8 being a carrier of haemophilia.
Individual 8 is a female and is a daughter of individual 1 and 2.
Individual 1 x individual 2

Transcribed Image Text:支
chis location.
XHXh x XHY
HX
XHXH normal female
SHXh normal but carrier female
HX
Completed forms to be made available for external moderation.
4.
AHX
normal male
Haemophilic male
Ihus the probability that individual 8 is a carrier is 50%.
4) Explain why only females can be carriers of haemophilia.
Haemophilia is a sex linked recessive disease suggesting that only females can be carrier and
not males because females carry two X chromosomes and males carry only one X
chromosome. The mutation in this disease occurs in the X chromosome. As the recessive
character is only expressed when both the Alleles in a gene are mutated so females usually do
not suffer with the disease but they can be carriers that is in them one allele is normal which is
dominant and one allele is recessive which is abnormal but in males there is only one X
chromosome and if it is mutated then he would be suffering from the disease and if it is not then
he would be normal. So no carriers for male.
Q8.
(1) Complete the following genetic diagram to show how parents who did not suffer from
haemophilia, could have a son wit
h haemophilia but also other children who did not suffer from haemophilia.
Phenotype of parents
Genotype of parents
Genotype of gametes
Normal male
Normal female
Genotype of offspring
Phenotype of offspring
What is the probability of the couple having a daughter with haemophilia?
(1)
What is the probability of the couple having another son with haemophilia?
(1)
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- Please asaparrow_forwardDirections: Use the following information to answer the questions below: all are sex-linked recessive disorders. H= normal blood clotting C=Normal Vision h-hemophilia muscular dystrophy M= Normal c= colorblind 1. Write the genotypes for the following individuals: a. female with no family history of hemophilia b. male with hemophilia c. male with muscular dystrophy d. male with normal color vision e. normal color vision female with colorblind father f. male with normal blood clotting g. colorblind male m= 2. Cross a female who is a carrier of the gene for hemophilia with a man who has normal blood clotting. Tell the expected phenotypic ratio of the offspring. 3. Cross a female with normal color vision, but whose father was colorblind, with a man who has colorblindness. Tell the expected phenotypic ratio of the offspring. 4. Cross a woman who does not suffer from muscular dystrophy and has no family history of muscular dystrophy with a man who has the disorder. Tell the expected…arrow_forwardStation 4: Pedigrees inidoned : no Pattern of inheritance (monohybrid, dihybrid, sex-linked, and genetically linked genes) can often be predicted from data, including pedigree, that give the parent genotype/phenotype and the offspring genotypes/phenotypes. III I II 1. Identify the type of inheritance in each of the following pedigrees(autosomal dominant, autosomal recessive, sex linked) AND EXPLAIN why it is that type of inheritance 20 2 21 O O 2. The pedigree below shows a family with a history of a recessive disease. DETERMINE the genotype of each individual for an autosomal traitarrow_forward
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