Copyright 2006 Nature Publishing Group Nature Reviews | Genetics Copyright © 2006 Nature Publishing Group Nature Reviews | Genetics The microscope image above shows the human chromosomes from a white blood cell. To create the image, researchers put cells in culture under conditions that encourage the cells to divide. They bathed the cells in a hypotonic (low salt) solution, which caused the cells to swell until their plasma membrane burst open. They "squashed" the chromosomes to spread them out, and stained them with a dye to make them visible under the microscope. Human chromosomes are numbered from longest (1) to shortest (22) plus the sex chromosomes X and Y. In the image chromosome 1 is about 7 micrometers. Answer the following questions. 1) What word(s) in the description above indicates that the chromosomes are not from a cell undergoing meiosis? 2) Based on the size, shape and appearance of the chromosomes in the image, in what cell cycle stage was the cell that the chromosomes came from? How can you tell? 3) Does the image suggest that centromere sequences are always located in the middle of a chromosome? Why or why not? 4) For the chromosomes in the image, can you narrow down which ones might be homologous? Why or why not?

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Copyright 2006 Nature Publishing Group
Nature Reviews | Genetics
Copyright © 2006 Nature Publishing Group
Nature Reviews | Genetics
The microscope image above shows the human chromosomes from a white blood cell. To create the
image, researchers put cells in culture under conditions that encourage the cells to divide. They
bathed the cells in a hypotonic (low salt) solution, which caused the cells to swell until their plasma
membrane burst open. They "squashed" the chromosomes to spread them out, and stained them
with a dye to make them visible under the microscope. Human chromosomes are numbered from
longest (1) to shortest (22) plus the sex chromosomes X and Y. In the image chromosome 1 is about
7 micrometers.
Answer the following questions.
1) What word(s) in the description above indicates that the chromosomes are not from a cell
undergoing meiosis?
2) Based on the size, shape and appearance of the chromosomes in the image, in what cell cycle
stage was the cell that the chromosomes came from? How can you tell?
3) Does the image suggest that centromere sequences are always located in the middle of a
chromosome? Why or why not?
4) For the chromosomes in the image, can you narrow down which ones might be homologous?
Why or why not?
Transcribed Image Text:Copyright 2006 Nature Publishing Group Nature Reviews | Genetics Copyright © 2006 Nature Publishing Group Nature Reviews | Genetics The microscope image above shows the human chromosomes from a white blood cell. To create the image, researchers put cells in culture under conditions that encourage the cells to divide. They bathed the cells in a hypotonic (low salt) solution, which caused the cells to swell until their plasma membrane burst open. They "squashed" the chromosomes to spread them out, and stained them with a dye to make them visible under the microscope. Human chromosomes are numbered from longest (1) to shortest (22) plus the sex chromosomes X and Y. In the image chromosome 1 is about 7 micrometers. Answer the following questions. 1) What word(s) in the description above indicates that the chromosomes are not from a cell undergoing meiosis? 2) Based on the size, shape and appearance of the chromosomes in the image, in what cell cycle stage was the cell that the chromosomes came from? How can you tell? 3) Does the image suggest that centromere sequences are always located in the middle of a chromosome? Why or why not? 4) For the chromosomes in the image, can you narrow down which ones might be homologous? Why or why not?
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