Which of the following statements are FALSE?     a A compound is an inhibitor of Glyceraldehyde 3-phosphate Dehydrogenase. If this compound were added to liver cells where D-Glucose was the only substrate one should observe an accumulation of intermediates from Glucose 6-phosphate to Glyceraldehyde 3-phosphate and a depletion of those from 1-3-Bisphosphoglyceric Acid to Pyruvate. b If the substrate for liver cells (above problem) were L-Lactate there should be no effect on the concentrations of glycolytic intermediates with the exception being a potential increase in the concentration of Pyruvate. c When Glucose is converted to lactate there is no overall change in the oxidation state because Glyceraldehyde 3-phosphate Dehydrogenase oxidizes Glyceraldehyde 3-Phosphate to 1-3-Bisphosphoglyceric Acid but Lactate Dehydrogenase reduces Lactic Acid to Pyruvate. d If all the glycolytic enzymes were added to a mixture of ATP + ADP + NAD+ and Glucose the product Pyruvate would be produced. e If a molecule of Glucose produces 2 molecules of ATP by substrate-level phosphorylation of ADP in Glycolysis and the resulting 2 molecules of pyruvate can each yield 15 molecules of ATP under aerobic conditions then 5 molecules of Glucose will produce 150 molecules of ATP. f Two molecules of Glucose will yield more ATP via substrate phosphorylation than one molecule of Sucrose. g Under anaerobic conditions 80 molecules of Glucose are required to produce 160 molecules of ATP.  h Under aerobic conditions 5 molecules of Glucose will give rise to 15 molecules of CO2.  i When Glucose is metabolized by yeast under anaerobic conditions 4 of the 6 carbons are found in Ethyl Alcohol and two are found as CO2.

ATP, like ADP and AMP, is a competitive inhibitor of NADH binding to malate dehydrogenase. Provide a structural explanation for this inhibition.

Alpha-ketoglutarate dehydrogenase exhibits feedback inhibition by

In 1937, two German biochemists published a paper proposing these reactions as part of glucose oxidation: citrate → isocitrate → α-ketoglutarate →succinate → fumarate → malate → oxaloacetate. Adding succinate, fumarate, or malate to thin slices of tissue increased oxygen consumption, supporting the hypothesis that these molecules are intermediates in the process. However, they were puzzled by the observation that these intermediates were still present in the reaction mixture at the end of the experiment. They had thought that intermediates would be consumed as they were converted to the next molecule in the pathway. What explains the observation that these intermediates were still present? a) The pathway is a cycle, constantly regenerating intermediates as glucose is broken down. b) Succinate, fumarate, and malate are not reactants but catalysts, and catalysts are not consumed in the process. c) Succinate, fumarate, and malate increase metabolism and therefore oxygen consumption,…