Based on the observed inheritance pattern and ratio of phenotypes, what are the genotypes of the affected children? Select an answer and submit it. For keyboard navigation, use the up/down arrow keys to select an answer. a) If c- = Cystic Fibrosis, the children are c-/c-. b) If c- = Cystic Fibrosis, the children are C/C. c) If c- = Cystic Fibrosis, the children are C/c-. d) If c- = Cystic Fibrosis, the children are C

Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN:9781305251052
Author:Michael Cummings
Publisher:Michael Cummings
Chapter5: The Inheritance Of Complex Traits
Section: Chapter Questions
Problem 23QP: If diseases such as cardiovascular disease (hypertension and atherosclerosis) are familial, is this...
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Based on the observed inheritance pattern and ratio of phenotypes, what are the genotypes of the affected children?
Select an answer and submit it. For keyboard navigation, use the up/down arrow keys to select an answer.
a) 
If c- = Cystic Fibrosis, the children are c-/c-.
b)
If c- = Cystic Fibrosis, the children are C/C.
c)
If c- = Cystic Fibrosis, the children are C/c-.
d)
If c- = Cystic Fibrosis, the children are C.
Expert Solution
Introduction:
  • Mutations in the CFTR gene lead to the genetic condition known as cystic fibrosis (CF).
  • The CFTR gene encodes a cystic fibrosis transmembrane conductance regulator (CFTR) protein that controls the movement of salt and water into and out of cells.
  • Mutations in the CFTR gene result in the production of a dysfunctional or absent protein, which causes typical CF symptoms.
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