Based on the intermediates outlined below, suggest why in different solvents and at different pH they are either soluble or insoluble.

Biochemistry
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Chapter1: Biochemistry: An Evolving Science
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Based on the intermediates outlined below, suggest why in different solvents and at different pH they are either soluble or insoluble.

Experiment 4 – The Wittig Reaction (Pg 35-37)
SL25
PPH3
NaOH(aq)
HO,
HO
Br
Ph3P.
H2C
H.
(then work-up)
O Na
O Na O
Nuc
Sub'n
HO
Nuc
Add'n
Br
Acid-base
Br
Ph3P.
Ph3P.
Ph3P.
Na
Ph
нн
OH
H ft
Ph
phosphonium salt
Na
Na®
Acid-base
Ph3P-
Transcribed Image Text:Experiment 4 – The Wittig Reaction (Pg 35-37) SL25 PPH3 NaOH(aq) HO, HO Br Ph3P. H2C H. (then work-up) O Na O Na O Nuc Sub'n HO Nuc Add'n Br Acid-base Br Ph3P. Ph3P. Ph3P. Na Ph нн OH H ft Ph phosphonium salt Na Na® Acid-base Ph3P-
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