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- 66. On this spirogram from a 25-year-old patient, the functional residual capacity is represented by the sum of which of the following? OA) Y+Z B) W+X+Y C) X+Y+Z OD) W+X+Y+Z and for the paBicillin CR is given IM. There are 600,000 units/mL in each syringe and the dose is 1.5 million units (1,500,000 units). What volume is to be administered?The growth of hybridoma cells, producing a monoclonal antibody, was monitored for 4 and a half days, and the results obtained are listed in the following table: time (days) nº cel/mL x 106 ln nº cel 0 0,45 -0,79851 0,2 0,52 -0,65393 0,5 0,65 -0,43078 1 0,81 -0,21072 1,5 1,22 0,198851 2 1,77 0,57098 2,5 2,13 0,756122 3 3,55 1,266948 3,5 4,02 1,391282 4 3,77 1,327075 4,5 2,2 0,788457 What is the maximum specific rate (µmax) of growth of these cells per day? what is the doubling time of these cells (in days)?
- What is the best anticoagulant for blood? Explain.A 43-year-old patient suffering from frequent urination and dry tongue was asked by the doctor to analyze RBS, HBA1¢ and GTT. Results were as follows: RBS = 45 mg\dl 2h GTT = 250 mg\dl HbA1c = 7.5% What interpretation of the result?Explain why serum is preferred over plasma in most clinical chemistry assays. Describe how the following anticoagulants prevent clotting. a.) Sodium or lithium heparin b.) EDTA c.) Sodium citrate
- A.How much of 10,000x SYBR safe would you add to 50 ml to make a final concentration of 1x? B.How will you set up the serial dilution? How many tubes do you need? What is the concentration in each? How much LB will you add to each tube? What volume of cells will you add?Mrs B, aged 43 years, weight 56 kg, requires a loading dose of drug B. The target plasma concentration is 18.9 mg/ L, volume of distribution is 0.5 L/ kg, the salt factor is 0.9 and bioavailability fraction is 1. What is the intravenous loading dose (LD) of Drug B in milligrams (mg)? units - mg LD = Cp desired x Vd S x F Where Cp desired is the target plasma concentration; Vd is the volume of distribution; S is the salt factor and F is the bioavailability fractionIdentify three other methods commonly used to visualize lipids on a TLC plate. Specify the type or class of lipids that are detected using these methods.
- CW is a 74-year-old male patient (65kg) was recently admitted to a hospital due to severe COVID-related pneumonia. He had impaired renal function based on the lab result on the day of his hospital admission, as his serum creatinine (SCr) concentration was 3.6 mg/dL (normal range is 0.74 to 1.35 mg/dL). He was to receive vancomycin for the severe pneumonia. The normal/usual dose of vancomycin is 1 g IV every 12 hours. Using Cockcroft-Gault equation, the elimination rate constant table and the nomogram, calculate the following: a) Adjusted dose of vancomycin based on his creatinine level, while keeping the dosing frequency constant.b) Adjusted dosing interval of vancomycin (tau) based on his creatinine level, while keeping the dose constant.A single dose of 300mg of drug is 63% bioavailable by the IM route. The same drug is 42% bioavailable by the oral route. How many 150mg tablets would need to be administered PO BID to achieve plasma levels comparable to the IM dose?After oral administration of single 250 mg capsule of an antihypertensive drug to a normal volunteer, the total calculated AUC was 50 mg.hr/L. After intravenous bolus administration of 100 mg, the AUC was 100 hr/L. explain the way plz What is the the absolute bioavailability of the drug from the tablet applied orally? (10. SLAYT) A) 60 % B) 20 % C) 50 % D) 75 % E) 40 %