Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN: 9780134580999
Author: Elaine N. Marieb, Katja N. Hoehn
Publisher: PEARSON
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An intravenous injection of potassium can cause death within a minute. From what you have learned about the resting membrane potential and action potential in chapter 7, how do you think it interferes with cellular function to cause death so fast?
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- Place the following events in chronological order from 1-8: Nat enters the cell, and depolarization occurs to approximately +30 mV. The voltage across the cell membrane is -70 mV, the resting membrane potential. Upon reaching the peak of the action potential, the VG Nat channels are inactivated by the closing of their inactivation gate and the activation gate of each VG K channel opens. VG K channels close by the closing of their activation gate, and the resting membrane potential is gradually restored. An excitatory post-synaptic potential depolarizes the membrane to threshold and the activation gate of VG Nat channels open. Upon returning to the resting membrane potential, VG Na channels are reset by opening of the inactivation gate and the closing of the activation gate. VG K+ channels are slow to close, resulting in an excess of K* efflux and hyperpolarization. Depolarization occurs as K+ flows out of the cell.arrow_forwardAcetylcholine is an excitatory neurotransmitter that is responsible for initiating muscle movement. Consider the scenario where a mouse was bitten by a snake that injected venom into their circulatory system. The venom has an inhibitory effect on the reuptake of acetylcholine from the synaptic cleft. Explain how the mouse’s body would respond to the venom as well as the venoms effect at the cellular level.arrow_forwardA taser is a device used by police to control unruly criminals by delivering a large electrical current into the body. This electrical current is able to temporarily paralyze the criminal. A Biology 30 student hypothesizes that this temporary paralysis is caused by the neurons in the body all simultaneously becoming unable to engage in a refractory period. Do you agree or disagree with this statement? Provide your rationale from the point of view of Na+ ion and K+ ion movement OR from the point of view of processes that do or do not occur properly in the criminal's neural synapses.arrow_forward
- The table of neurotransmitters below is too simplistic. In reality, one neurotransmitter chemical has multiple actions in the nervous system. How is this possible?arrow_forwardA resting cell's membrane is more permeable to K+ simply because: K has a higher atomic number than Na. The Na+/K+ ATPase only works in response to a stimulus. There are more voltage-gated K+ channels than voltage-gated Na+ channels in the cell membrane. There are more K+ leaky channels than Na+ leaky channels in the cell membrane.arrow_forwardFill in the diagram, your illustration should demonstrate for each phase of the AP: 1. The relative concentration of K and Na 2. The relative voltage across the membrane 3. Any movement across the membrane of K and NA 4. The three kinds of channels in the membrane, and their state (open or closed) 5. Finally, indicate on the graph of the AP which phases correspond to hyper- polarization and which phases correspond to de- polarization Outside Outside Inside Inside Outside Inside Outside 1 Outside Inside Insidearrow_forward
- Antiseizure drugs stop seizures from happening by inhibiting electrical impulses. What is the importance of sodium and calcium channels on a neuron and reasons why actions potentials do not occur when these channels are inhibited.arrow_forwardNervous cells use both chemical and electric communication mechanisms, whereas the endocrine system typically uses for communicationarrow_forwardDraw and discuss an AP (action potential). Below this graph draw and discuss the conductance of the important ions moving across this membrane that makes the action potential work. a. Cardiac fiber (non automatic cells) b. SA (self excitable cells)arrow_forward
- What is the difference between the membrane potential in a normal cell and an excitable cell?arrow_forward37) Multiple sclerosis is a disease in which the body attacks its own nervous system and specifically affects the myelin. Its many symptoms include a person having a reduced sense of touch. Explain how the disease effects the conduction of information and what class of neurons appears to be affected to cause this symptom.arrow_forwardWhat can occur to the neurotransmitter after being released from the synaptic vesicle? Give a real life example of this.arrow_forward
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