An accumulation in mutations in genes involved in _______ and _______ may lead to cancer.     cell division and DNA synthesis     telomere maintenance and DNA synthesis     DNA damage response and nucleosome formation     DNA damage response and cell cycle checkpoints

All of the following are stages of mitosis except _________. a. prophase b. interphase c. metaphase d. anaphase

After mitosis, each daughter cell contains genetic instructions that are ______ and _____ chromosome number of the parent cell. a. identical to the parent cells; the same b. identical to the parent cells; one-half the c. rearranged; the same d. rearranged; one-half the

Figure 10.6 Which of the following is the correct order of events in mitosis? Sister chromatids line up at the metaphase plate. The kinetochore becomes attached to the mitotic spindle. The nucleus reforms and the cell divides. Cohesin proteins break down and the sister chromatids separate. The kinetochore becomes attached to the mitotic spindle. Cohesin proteins break down and the sister chromatids separate. Sister chromatids line up at the metaphase plate. The nucleus reforms and the cell divides. The kinetochore becomes attached to the cohesin proteins. Sister chromatids line up at the metaphase plate. The kinetochore breaks down and the sister chromatids separate. The nucleus reforms and the cell divides. The kinetochore becomes attached to the mitotic spindle. Sister chromatids line up at the metaphase plate. Cohesin proteins break down and the sister chromatids separate. The nucleus reforms and the cell divides.

How can errors in the cell cycle lead to cancer in humans?

In the cell cycle, at which stages do two chromatids make up one chromosome? a. beginning of mitosis b. end of G1 c. beginning of S d. end of mitosis e. beginning of G2

Figure 10.13 Rb and other proteins that negatively regulate the cell cycle are sometimes called tumor suppressors. Why do you think the name tumor suppressor might be appropriate for these proteins?

Chromosomes are duplicated during what portion of the cell cycle? a. G 1 phase b. S phase c. prophase d. prometaphase

Which of the following mutations will result in cancer? a. homozygous recessive mutation in a tumor-suppressor gene coding for a nonfunctional protein b. dominant mutation in a tumor-suppressor gene in which the normal protein product is overexpressed c. homozygous recessive mutation in which there is a deletion in the coding region of a proto-oncogene, leaving it nonfunctional d. dominant mutation in a proto-oncogene in which the normal protein product is overexpressed

Name the four main stages of mitosis, and describe what happens in each stage.