Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN: 9780134580999
Author: Elaine N. Marieb, Katja N. Hoehn
Publisher: PEARSON
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## Characteristics of DNA in Cancer Cells ### Question: What describes the DNA of cancer cells? ### Instructions: Select all that apply. - [ ] Often single stranded instead of double stranded - [x] Often contains mutations that affect DNA polymerase genes - [ ] Often contains more than one different mutation - [ ] Often contains mutations that affect genes involved in the cell cycle In understanding the nature of cancer cell DNA, it is important to recognize the following characteristic: **Mutations in DNA Polymerase Genes:** Cancer cells often contain mutations that specifically affect DNA polymerase genes. The DNA polymerase is an enzyme responsible for the replication of DNA and repair. When this enzyme is mutated, it can lead to errors in DNA replication and a higher likelihood of additional mutations, contributing to the uncontrolled cell growth observed in cancer. ### Incorrect Options - **Often single stranded instead of double stranded:** Cancer cell DNA remains double-stranded like normal cell DNA. - **Often contains more than one different mutation:** While cancer cells can have multiple mutations, it is not exclusive to them. This is not a defining feature. - **Mutations affecting genes involved in the cell cycle:** Although mutations affecting the cell cycle are common, this characteristic alone does not comprehensively describe the DNA of cancer cells.
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Transcribed Image Text:## Characteristics of DNA in Cancer Cells ### Question: What describes the DNA of cancer cells? ### Instructions: Select all that apply. - [ ] Often single stranded instead of double stranded - [x] Often contains mutations that affect DNA polymerase genes - [ ] Often contains more than one different mutation - [ ] Often contains mutations that affect genes involved in the cell cycle In understanding the nature of cancer cell DNA, it is important to recognize the following characteristic: **Mutations in DNA Polymerase Genes:** Cancer cells often contain mutations that specifically affect DNA polymerase genes. The DNA polymerase is an enzyme responsible for the replication of DNA and repair. When this enzyme is mutated, it can lead to errors in DNA replication and a higher likelihood of additional mutations, contributing to the uncontrolled cell growth observed in cancer. ### Incorrect Options - **Often single stranded instead of double stranded:** Cancer cell DNA remains double-stranded like normal cell DNA. - **Often contains more than one different mutation:** While cancer cells can have multiple mutations, it is not exclusive to them. This is not a defining feature. - **Mutations affecting genes involved in the cell cycle:** Although mutations affecting the cell cycle are common, this characteristic alone does not comprehensively describe the DNA of cancer cells.
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