An 85-year old man was recently admitted to a nursing facility. Diseases listed in his medical record on admission were depression with anxiety symptoms, atrial fibrillation, chronic obstructive pulmonary disease, and osteoarthritis. Medications taken orally by the patient included the following: Sertraline (base, pKa = 9.5) Diazepam (base, pKa = 3.0 Amiodarone (base, PKa = 7.4) Theophylline (acid, pKa = 8.8) Ibuprofen (acid, pKa = 4.8) Shortly after administration, which of the following drugs was most likely concentrated inside the gastric cells? Explain.

An 85-year old man was recently admitted to a nursing facility. Diseases listed in his medical record on admission were depression with anxiety symptoms, atrial fibrillation, chronic obstructive pulmonary disease, and osteoarthritis. Medications taken orally by the patient included the following: Sertraline (base, pKa = 9.5) Diazepam (base, pKa = 3.0 Amiodarone (base, PKa = 7.4) Theophylline (acid, pKa = 8.8) Ibuprofen (acid, pKa = 4.8) Shortly after administration, which of the following drugs was most likely concentrated inside the gastric cells? Explain.

Principles Of Pharmacology Med Assist

6th Edition

ISBN:9781337512442

Author:RICE

Publisher:RICE

Chapter23: Medications Used For Cardiovascular System Disorders

Section: Chapter Questions

Problem 6RQ

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