Aldosterone is a hormone involved in maintaining fluid balance in the body. In a veterinary study, six dogs with heart failure were treated with the drug Captopril, and plasma concentrations of aldosterone were measured before and after the treatment. The results are given in the table below.34 Consider a sign test, using a nondirectional

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Aldosterone is a hormone involved in maintaining fluid balance in the body. In a veterinary study, six dogs with heart failure were treated with the drug Captopril, and plasma concentrations of aldosterone were measured before and after the treatment. The results are given in the table below.34 Consider a sign test, using a nondirectional alternative, to investigate the claim that Captopril affects aldosterone level.

Animal
Before
After
Difference
1
749
374
375
2
469
300
169
3
343
146
197
4
314
134
180
286
69
217
6.
223
20
203
Mean
397.3
173.8
223.5
SD
190.5
136.4
76.1
a. What is the value of the test statistic?
b. The P-value for the sign test is 0.031. If a = 0.10, what is your
conclusion?
LO
CO
Transcribed Image Text:Animal Before After Difference 1 749 374 375 2 469 300 169 3 343 146 197 4 314 134 180 286 69 217 6. 223 20 203 Mean 397.3 173.8 223.5 SD 190.5 136.4 76.1 a. What is the value of the test statistic? b. The P-value for the sign test is 0.031. If a = 0.10, what is your conclusion? LO CO
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