ACH ACH + ACH + ACH + 1 x 10-M 3 x 10-M Acetylcholine Alone Concentration [Molar] Homatropine Homatropine Homatropine 3 x 10-⁹M 3 x 109 3 +/- 1 6 x 10-9 8 +/- 3 No response 3 x 10-8 28 +/- 6 10 +/- 4 No response 6 x 10-8 38 +/-8 21 +/-9 5+/-2 No response 3 x 10-7 55 +/- 5 43 +/- 7 27 +/-9 10 +/- 4 6 x 107 56 +/- 5 52 +/-3 38 +/- 7 20 +/- 7 3 x 10-6 55 +/- 4 53 +/- 6 43 +/- 6 6 x 106 56 +/- 2 54 +/- 5

Below are responses generated using the isolated guinea-pig ileum preparation to determine a pA2 value for the cholinergic antagonist homatropine.Responses are expressed in millimetres +/- SDM (n = 4).1. Plot the data on a sheet of paper and then determine by Schild analysis the pA2 value and Schild slope 2. show all calculation on a table form on a sheet of paper 3. discuss the result with conclusion

The concentration of acetylsalicylic acid in an antipyretic tablet was determined by HPLC using a normal calibration curve. Standard solutions of acetylsalicylic acid were prepared and analysed using a 10µL loop. The results obtained for the standards are tabulated below: Conc. of Acetylsalicylic Acid (ppm); Signal (arbitrary units) 50; 6352 100; 12869 150; 19175 200; 25536 250; 31936 To determine the concentration of acetylsalicylic acid in an antipyretic tablet, 10 tablets were weighed (6.500 g total) and crushed to a fine powder using a mortar and pestle. A quantity of powder equal the mass of one tablet was added to a 100 mL volumetric flask. The tablet powder was dissolved with 20 mL of methanol and the flask was made to volume using water. The solution was filtered. A 1.000 ml aliquot was transferred to a 10 ml volumetric flask, which was then made to volume with water. Analysis was conducted using a Bio Sil HL C18, 250mm x 4.6mm column; 5um, with a mobile phase of acetonitrile:…

(2) Sally starts eluting her column with petroleum ether in hopes of separating her 50:50 ferrocene: fluorenone mixture. She notices her mobile phase getting low when there is limited separation between her two components. She eagerly adds more solvent to avoid her column from drying out. Sally then realizes she poured from her 1:1 petroleum ether: diethyl ether beaker rather than her petroleum ether beaker. (a) Using the molecular view below, explain how this would impact her product elution from the column. top of column H buret wall AI H H H H H H H H H H bottom of column buret wall (b) How does this error impact her experimental results? (c) Using pictures and words, how could Sally analyze the purity of her product? Fe