Biochemistry
9th Edition
ISBN: 9781319114671
Author: Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher: W. H. Freeman
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Question
According to the double-strand break model, does gene conversion
necessarily involve DNA mismatch repair? Explain.
Expert Solution
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introduction
Gene Conversion means a modification or conversion of one or two alleles of a gene by the other,
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Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biochemistry and related others by exploring similar questions and additional content below.Similar questions
- What type of repair would be used to fix a mutation that arises during replication and that escapes detection by polymerase proofreading mechanisms? What is the most likely reason that this mutation escaped correction during proofreading?arrow_forwardIn eukaryotes, what is meant by the term DNA replication licensing? How does the process occur?arrow_forwardExplain why a DSB-repair homologous recombination can occur between any two DNA molecules that share homology rather than only between two DNA molecules that carry a specific sequence.arrow_forward
- What are site-recombinases? Describe in detail how cre- recombinase can be used to decipher the roles of specific genes and proteins in complex multicellular organisms? Explain how the cre-lox system can be used to examine the role of a particular gene in a specific type of tissue?arrow_forwardHow does proofreading differ from later DNA repair mechanisms in terms of timing and the proteins involved?arrow_forwardThe occurrence of multiple transposons within the genome oforganisms has been suggested as a possible cause of chromosomalrearrangements such as deletions, translocations, and inversions.How could the occurrence of transposons promote these types ofstructural rearrangements?arrow_forward
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