a. NABH4 then H3o+ b. PBr3 c. Mg in dry ether, then CH2=O, then H30* d. Dess-Martin Periodinane e. CGH5CH,MgBr in dry ether, then H30* f. POCI3, pyridine CH2OH LĈH

Drug synthesis from Baeyer-Villiger Oxidation

1) For each reaction below, provide the product and type (ketone/aldehyde/enol/enolate) of the reactant and the product. The equilibrium arrows are generic: a) Type b) Type c) Type d) Type OH 0}₁ OH H3O* catalyst H₂O H3O* catalyst H₂O OH catalyst H₂O OH catalyst H₂O Product Type Product Type Product Type Product Type

Complete the following synthesis writing each step for the synthesis of the product showing all reactants and conditions

The following reaction can be carried out in two steps. Choose the correct reagents i) and ii) to perform the following reaction. CN i) 11) or Oi) CN; ii) heat Oi) CN ; ii) H₂O, acid catalyst O i) Br₂; ii) CN- O i) H₂O, acid catalyst; ii) CN O i) HBr; ii) CN

OH c) E1 Reaction type

Provide the major organic product of the following reaction. Ph Ph NH₂ NH₂ 1. NaN3 2. LIAIH₂ 3. H₂0

C₂H₂ C CH C₂H₂-CC-CH₂ C₂H₂ C-CH₂ H₂C 1) NaNiy 2) CH,Br 3) Hy/ Lindlar catalyst C₂H₂-CC-CH₂ C₂H-CC-NHCH, IV