A point mutation occurs in the middle of the coding sequence for agene. Which types of mutations—silent, missense, nonsense, andframeshift—would be most likely to disrupt protein function andwhich would be least likely?

Q: point mutations that affect the amino acid sequence of a protein include, frameshift mutations,…

A: ANSWER : Absolutely, let's delve into missense mutations and how they can influence protein…

Q: Why will a mistake in the RNA code alone not become a mutation?

A: A change in the genetic code is called a mutation when it becomes a permanent part of the genome of…

Q: Why might some cells in the body, such as those in bonemarrow, be more susceptible to ribosomal…

A: Mutation It is the sudden heritable changes happening in the genotype of the organism which is…

Q: Which of the following types of mutations, resulting in a change in the mRNA just after the…

A: The translation process will result in the creation of proteins. The process of protein synthesis is…

Q: Do you think each of the following types of mutationswould have very severe effects, mild effects,…

A: A modification in the sequence of the bases in DNA is referred to as a mutation. The mutation could…

Q: a. In your claim words, depict the contrast between ρ-dependent and ρ-independent end of translation…

A: ρ-dependent is basically a translation termination mechanism occuring in prokaryotic cells. Here ρ…

Q: Suppose part of the amino acid sequence of a protein is N... Gly-Ala - Pro-Arg-Lys ...C. Which of…

A: A frameshift mutation occurs when nucleotides are inserted or deleted from the DNA sequence, causing…

Q: 2a) Suppose you have a gene in which a single base substitution has created the nonsense mutation…

A: DNA(deoxyribonucleic acid) is the genetic material in all the organisms except few viruses. The…

Q: . The genetic code is thought to have evolved to maximize genetic stability by minimizing the effect…

A: Arginine is coded by six mRNA codons.

Q: Two possible point mutations are the substitution of lysine for leucine or the substitution of…

A: Amino acid mutations refer to changes in the DNA sequence that result in alterations to the sequence…

Q: The following RNA sequence represents a small messenger which can be translated in a prokaryotic…

A: The first step in translating an RNA sequence into a protein is to divide the sequence into codons,…

Q: Consider the following coding 71 nucleotide DNA template sequence (It does not contain a…

A: In cell protein formed according to the sequence on mRNA. mRNA is formed from DNA sequence by the…

Q: The codon change (Gly-12 to Val-12) in human rasH that convertsit to oncogenic rasH has been…

A: The codons are the triplet sequences of the nucleotides like DNA (deoxyribonucleic acid) and RNA…

Q: A reversion is a mutation that returns a mutant codon back to acodon that gives a wild-type…

A: A mutation is a change in the DNA sequence, either due to mistakes during DNA replication or because…

Q: Name the type of mutation from the following choices: silent, missense, nonsense, frameshift. The…

A: Mutations are sudden heritable changes in the nucleotide sequence of a gene that changes the amino…

Q: Gene editing is also used to explore the structure and function ofproteins. For example, changes can…

A: From the observations, it gets clear that the amino acid aspartate shows the most functional…

Q: Define FOUR (4) types of point mutations within coding sequences

A: Coding sequences are the sequence of nucleotides in DNA capable to produce a protein. Many mutations…

Q: The following DNA sequence is derived from the middle of an exon of a eukaryotic gene. This sequence…

A: The Central Dogma concept states that DNA is duplicated into DNA. RNA is formed from DNA and…

Q: mutant appear on a gel in comparison

A: Point mutations can cause serious changes to an organism if they change the way a protein works By…

Q: A gene contains eight sites where alternative splicing is possible. Assuming that the splicing…

A: Given :  A gene contains eight sites where alternative splicing is possible. To find : The splicing…

Q: Describe the steps necessary to synthesize mRNA fromeach of the following: double-stranded DNA,…

A: The synthesis mRNA from double-stranded DNA requires the enzyme RNA polymerase II, this enzyme will…

Q: What is the result of Frameshift mutations from the insertion or deletion of nucleotides within the…

A: Mutation, an alteration in the genetic material of a cell of a living organism or of a virus that is…

Q: A certain membrane protein is found on the ER membrane with the N-terminus on the ER side of the…

A: This question is about the orientation of a particular membrane protein within the endoplasmic…

Q: A normal polypeptide and a mutant of the polypeptide were hydrolyzed by an endopeptidase under the…

A: Chromatography is a useful technique to study the separation of amino acids. Paper chromatography is…

Q: name one kind of mutation that produces an altered protein. what determines wether the altered…

A: Genetic material is nothing but the sequence of nucleic acids which is called as DNA. It contains…

Q: Sickle-cell disease is caused by a so-called point mutation in the humanβ-globin gene. A point…

A: Two b-globin polypeptides combine with two a-globin polypeptides (encoded by another gene family)…

Q: Cystic fibrosis (CF) is an inherited disorder caused by different types of mutations, many of which…

A: CF is caused by a mutation in a gene called the cystic fibrosis transmembrane conductance regulator…

Q: Figure 2 illustrates a type of gene mutation.     a) State the type of gene mutation shown in…

A: Mutation  Mutation is the alteration in the original sequence of DNA. Mutation can be caused due to…

Q: (b) Hemoglobin is made of B-globin subunits. The first few mRNA nucleotides for B- globin are given…

A: RNA strnad given = 5'-AUGGUCCACCUGACUCCUGAGGAGAAG...UGA-3' (i) DNA strand from which this mRNA is…

Q: A polypeptide has the following amino acid sequence: Met-Ser-Pro-Arg-Leu-Glu-Gly The amino acid…

A: Mutation is defined as sudden inheritable change that occurs in the DNA sequence. It may be…

Q: 3'-TAC TGA GCA AGA TTA CAT ACT-5' Write down the mRNA sequence for the given DNA sense strand…

A: A mutation in both copies of the HBB gene results in sickle cell disease (SCD), a hereditary…

Q: What three different types of mutations involve changes in a single base, and what effect can each…

A: DNA is the genetic material in living organisms. It contain genes that is responsible for determine…

Q: Breast cancer can be caused by a genetic mutation on the BRCA1 gene changing a methionine to an…

A: BRCA 1 or Breast cancer type 1 susceptibility protein is a protein that in humans is a tumor…

Mitochondrial Mutations

A mitochondrion is a cellular organelle that serves as the site for cellular respiration and energy production (ATP or Adenosine Triphosphate). It is a double-membrane-bound organelle and is only present in eukaryotic cells.