A patient is O positive and his serum is agglutinating all screening and panel reagent cells at room temperature. His autocontrol is positive at room temperature also. The patient may have an antibody to a high incidence antigen. One possibility is that he may have a clinically insignificant autoanti-I. How could you prove that the patient has an anti-I antibody?

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A patient is O positive and his serum is agglutinating all screening and panel reagent cells at room temperature. His autocontrol is positive at room temperature also. The patient may have an antibody to a high incidence antigen. One possibility is that he may have a clinically insignificant autoanti-I. How could you prove that the patient has an anti-I antibody?

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