A nonsense mutation in a gene:   A. introduces a premature stop codon into the mRNA   B. changes an amino acid in the encoded sequence   C. has no effect on the amino acid sequence of the encoded protein   D. alters the reading frame of the mRNA

Alternative splicing allows for more proteins to be made from the same region of DNA; explain how you can get multiple proteins from the same DNA. Then explain if alternative splicing changes the DNA and/or the mRNA. Draw or diagram out an image to depict this.

what is the first event to take place in translation in eukaryotic cell? a. An clongation of the polypeptide chain by the addition of amino acids b. Binding of the larger ribosomal subunits to the smaller ribosomal subunits c. Base pairing of activated methionine-tRNA to AUG of messenger RNA d. The small subunits of ribosome recognizing and attaching to 5' cap of mRNA

The role of transfer RNA (tRNA) is to match a codon (3 bases) in mRNA sequence to:   A. An amino acid   B. A peptide bond   C. An R group   D. A start codon

Explain how the information in mRNA is converted into a fully folded protein, and how the misfolding of proteins can result in disease, giving an example of such a condition. please expain indded with example

A nonsense mutation is a mutation that creates a premature stop codon in the protein sequence. Based on our previous discussions on mutations and how they alter protein-coding sequences, explain how a nonsense mutation can lead to disease onset.

Such as in the case of sickle-cell disease, which of the following can occur from the mutation of just a single nucleotide pair in an organism’s DNA?   a. Altered mRNA strands   b. Altered primary protein structure   c. Altered tertiary protein structure   d. Altered protein function   e. All of the above