A mutation has occurred that results in phosphofructokinase not being able to bind ATP in its allosteric site. What impact will this mutation have on the production of ATP in the cell?   Select one: a. If no ATP can bind to the allosteric site, then phosphofructokinase will not be able to add the phosphate to fructose-6-phosphate to make fructose-1,6-bisphosphate and glycolysis will not work. So no pyruvate, not cellular respiration.  b. If ATP cannot bind to the allosteric site, phosphofructokinase will not be activated to make more ATP by substrate-level phosphorylation. c. No impact on the production but will not be able to effectively shut off over production of ATP with feedback inhibition.

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Mitochondrial Mutations

A mitochondrion is a cellular organelle that serves as the site for cellular respiration and energy production (ATP or Adenosine Triphosphate). It is a double-membrane-bound organelle and is only present in eukaryotic cells.