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- Which of the following class of chemicals exerts its effects by entering cells, binding intracellular receptors, and affecting gene expression? a. Peptides b. Steroids c. Bioactive amines d. Amino acids Studies have demonstrated biological differences between adult heterosexual and adult homosexual men. Which of the following has been shown to be different between these groups? a. different pattern of cortical neuron branching b. different testosterone levels c. different size of a hypothalamic nucleus d. different estrogen levelsA new antagonist molecule has been discovered that binds to and blocks plasma membrane receptors. What effect will this antagonist have on testosterone, a steroid hormone? a. It will block testosterone from binding to its receptor. b. It will block testosterone from activating cAMP signaling. c. It will increase testosterone-mediated signaling. d. It will not affect testosterone-mediated signaling.The action of steroid hormones is different from that of peptide hormones becausea. peptide hormones must enter the cell to begin action, whereas steroid hormones must begin action on the external surface of the cell membrane.b. steroid hormones must enter the cell to begin action, whereas peptide hormones must begin action on the external surface of the cell membrane.c. peptide hormones produce a hormone receptor complex that works directly on the DNA, whereas steroid hormones cause the release of a secondary messenger that triggers enzymes.d. None of these answers is correct.
- Recently, a Gα q-coupled receptor was discovered that mediates at least some of the many activities of estrogen. At the time, this discovery generated considerable controversy, as it ran counter to what was then the understanding of how steroid hormone signaling worked. Which of the following observations might have led the investigators to suspect the existence of this newly discovered receptor? A. Activities of estrogen apparent less than 1 minute after application of the hormone B. The growth promoting activity of estrogen C. The presence of estrogen nuclear receptors in cells not previously known to respond to the hormone D. Estrogen is found in much higher concentrations in adult women than adult men E. Uptake of estrogen by target cellsWhich of the following statements is truc a. Neurotransmitters must bind to a receptor to exert an action on a cell but hormones do not have to bind to a receptor to exert an action b. The nervous system effects are longer lasting than the endocrine system c. The nervous system effects are faster to respond than the endocrine system d. The nervous system releases neurotransmitters into the bloodstream similar to how the endocrine system releases hormones into the bloodstreamA loss of function mutation in a gene encoding a SNARE protein would result in which of the following effects? оа. The anterior pituitary would be unable to release its hormones o b. Skeletal muscle cells, but not cardiac or smooth muscle, would lose their ability to contract O c. Neural cells would be unable to generate action potentials d. Neural cells would be unable to transmit action potentials via electrical synapses Neural cells would be unable to transmit action potentials via chemical synapses O e.
- The figure at right presents a schematic of an endocrine pathway that regulates testosterone production. The arrows and the cylinder indicate transport of a chemical messenger in the circulatory system. In this pathway, luteinizing hormone... A. Is a tropic neurohormone B. Regulates the synthesis of a peptide hormone C. Is released in response to a tropic neurohormone D. Is synthesized on demand E. None of the above Gonadotropin releasing hormone Hypothalamic neuron Luteinizing hormone testosterone Anterior pituitary cell Steroidogenic cell Target tissue cellJohn is told that he has a hormone receptor problem and his cells are not responsive to hormone stimulation. Which of the following is a possible reason for his problem? Select one: A. He has an ectopic tumor. B. He has hypersensitivity to the hormone. C. He has a receptor that has been overstimulated. D. He has too many receptors for the hormone. E. He has antibodies that block the function of the hormone receptor. O O O Owhat happens to a water souble hormone after it binds to a receptor on the target cell? select all that apply A. the hormone unbinds the receptor or pops back off B. the hormone is broken down by an enzyme C. the hormone is transported into the cell where it is destroyed by enzymes d. the hormones is transported into the cell where it promotes transcription.
- Different cell-types can use the same receptor-type to detect a common hormone, which leads to the abilitiy of that hormone to trigger multiple physiological responses. A. True B. Falsewhich of the following happens when a therapeutic synthetic homone is introduced intno the body to treat patients natural hormone insufficiency?(select all that apply) A. The target cell responds the same way as when the hormone is natural B. the synthetic hormone has no effect on the target tissues C. the amount of natural hormone produced by the patients body declines D. the synthetic hormone is destroyed before it can have an effect on the target tissue.In relation to Cushing’s Syndrome, a method that some scientists have used to treat the disease is to use small molecules that bind to, but do not activate, MC2R. This type of molecule is considered an antagonist. How can an antagonist bind to the same receptor as ACTH but not activate it ? a. The antagonist binds covalently while ACTH binds non covalently b. The antagonist is only partially complimentary to the binding pocket of MC2R c. The antagonist binds to ACTH and blocks it from binding to the receptor properly d. The antagonist is the exact same structure as ACTH but since it is synthetic it doesn’t work
