A diagram of an antibody IgG molecule is given below. Indicate the locations of the following items on the diagram by putting the letter next to those parts of the molecule. If a part occurs more than once, mark all copies of the part. If you want you can draw the structure, mark it, take a picture, and insert the photo. (a) (b) (c) (d) the heavy chains the light chains the antigen binding site(s) the hinge region the Fc region

For Western Blot detection of specific proteins, the secondary antibody directly binds to: A) The antigen-binding sites of the primary antibody B) The protein of interest on the membrane C) The Fc domain of the primary antibody

In a mixed lymphocyte reaction, T cells from individual A make a robust response to antigen-presenting-cells from individual B, as long as the two individuals express different alleles of MHC molecules. Estimates indicate that up to 10% of the T cells from individual A may contribute to this response. If one performed this assay using responder T cells from a child and antigen-presenting cells from one parent, the result would be:          A massive proliferative response made by the antigen-presenting cells of the parent A very weak response by the child’s T cells, involving only 0.1% of their T cells The complete absence of any proliferative response by the child’s T cells A robust cytolytic response that kills all of the parent’s antigen-presenting cells A robust response by the child’s T cells

The antibody surface involved in antigen binding varies depending on the size and nature of the antigen. This surface can be concave or flat, and sometimes, can have extended protrusions. This is accomplished by: Flexibility in the hinge regions of the antibody allowing rotation of the antigen-binding sites Some antibodies using V region framework sequences instead of the CDRs to bind antigen The ability of different CDR sequences to form many structurally distinct shapes and surfaces The ability of the same heavy chain to pair with different light chains The differential usage of κ versus λ light chains, as κ chains form concave

After observing the following image, you can make which of the following statements? Choose from the following: (A) antibody A reacted with antigen A (B) antibody B reacted with antigen B (C) Rh antibody reacted with Rh antigen (D) none of the above occured

Antigens include proteins, polysaccharides, and various small molecules that stimulate antibody production. True or False?

Describe how the B-cell receptor (BCR) differs from an antibody. Draw a generic example of each and point out the difference between them.

Please answer part b in detail, thanks

Draw a well-labelled diagram of an antibody molecule.

Define the term: antibody