A 56-year-old Asian man with hypertension, hypercholesterolemia, and type 2 diabetes mellitus comes to a physician for a check-up. It has been several years since he has been to the doctor. His past medical history is significant for an acute illness at the age of nine, which involved a high fever, pleuritic chest pain, migrating joint pain, and a pink, nonpruritic rash on his torso. His blood pressure is 155/100 mm Hg and heart rate is 70/min. Auscultation of the heart reveals a low-pitched diastolic rumble heard best at the apex. What is the most likely pressure change that would be seen in this patient’s heart?
(A) Decreased left atrial pressure
(B) Decreased left ventricular pressure
(C) Increased left atrial pressure
(D) Increased left ventricular pressure
(E) Increased right atrial pressure
to generate a solution
a solution
- James Dunn is a 40-year-old African American man. He presents to the physician’s office today complaining of headache. His vital signs during triage are as follows: blood pressure 165/90 mm Hg, heart rate 80 beats/minute, temperature 98.5F, weight 125 kg (275 lb), and height 5 ft 11 in. He currently has no other diagnosed medical conditions. The physician gives Mr. Dunn a prescription for lisinopril/hydrochlorothiazide (Prinzide) 10/12.5 mg with directions to take one tablet by mouth daily in the morning. (Learning Objectives 1, 3, 4, 8) 1. In which stage of hypertension would you place Mr. Dunn? 2. What lifestyle modifications should Mr. Dunn be encouraged to follow? 3. What class of antihypertensive is lisinopril/hydrochlorothiazide? 4. What would you tell Mr. Dunn about his new medication?arrow_forward83. A 25-year-old woman comes to the physician because of a 2-week history of left flank pain. She has had progressive weakness and decreased appetite during this period. Her temperature is 38°C (100.4°F). Physical examination shows left flank tenderness. Laboratory studies show a leukocyte count of 18,500/mm³. Urinalysis shows numerous RBCs and WBCs. A CT scan of the abdomen confirms an abscess of the lower pole of the left kidney. Which of the following is most likely preventing the spread of the infection to the surrounding organs? A) Fatty layer (Camper fascia) of the abdominal tela subcutanea B) Greater omentum C) Membranous layer (Scarpa fascia) of the abdominal tela subcutanea D) Pararenal fascia E) Perirenal (Gerota) fasciaarrow_forwardApart from suffering from recurrent and prolonged infections, Marie Curie experienced the following signs and symptoms: fatigue, rapid heart rate, pale skin, easy bruising, prolonged bleeding from cuts, and dizziness. Bone marrow transplant was not an option at that time and so blood transfusion was the treatment of choice. Please explain the reasoning behind these other signs and symptoms that Curie experienced? Thank you!arrow_forward
- Question:- A 25-year-old man comes to the emergency department because of a 2-day history of fever and rash. He has a history of complex partial sezure secondary to an arteriovenous malformation. He has had breath through seizure several times each despite treatment with several medication regions. Initially, treatment with phenytoin, which caused sedation. Two weeks ago, he was stitched to valproic acid and lamotrigine. He states that he has not had any seizure during topiramate and phenytoin, which caused sedation. Two weeks ago, he was switched valproic acid and lamotrigine. He states that he was not ad nay seizure during this time, and he finished his sample package of lamotrigine. He is awake and alert but appears ill. Vital signs are temperature 39.0 oC (102.2 oF), pulse 1110/min, respiration 22/min. and blood pressure 130/90 mm Hg. Examination shows extensive bullae, especially over the hands and feet. There are erosive lesions over the mouth and genital area. Which of the…arrow_forwardA 60-year-old woman with anemia is admitted to the hospital. Her hematocrit is 17% and she has been experiencing subtle gastrointestinal bleeding over many weeks. Her physician requests 4 units of red blood cells for transfusion. The patient’s RBCs phenotyped as group AB, D-positive. Her antibody screen is negative on the sample drawn in the emergency room, but her records indicate a previously detected anti-E. Only three group AB, D-positive red blood cell units are available in the blood bank’s inventory. The blood bank’s inventory contains RBC donor units of all ABO and D types.Having located 6 E-negative donor units, you perform crossmatching on the units. One of the units is incompatible in the antiglobulin phase (2+). The physician is becoming insistent on beginning the transfusion, since the patient is having some shortness of breath.How do you respond to the physician’s request?List several reasons to explain the one incompatible donor unit.What additional testing do you…arrow_forwardrash in this patient and 1) what is the name given to this type of rash? 2)Describe the red blood cell morphology in the blood film. 3) Describe the white blood cell morphology in the blood film. 4) What is the name given to this the type of anaemia present in this case? 5) Taking into consideration the clinical presentation, the full blood count results and the red blood cell morphology, what is your provisional diagnosis for this case? give right accurate answer only د A 3-year-old male presents to ED with bloody diarrhoea and a rash. Full blood count results and blood film Parameter Result Reference range Haemoglobin 92 g/L 110-140 g/L Red blood cell count 3.58 x 102/L 3.86-5.00 x 102/L Haematocrit 0.28 0.31-0.38 Mean cell volume 78.5 fL 73-85 fl Mean cell haemoglobin 25.7 pg 25-30 pg MCHC 327 g/L 310-360 g/L Reticulocyte count 150 x 10%/L 20-80 x 10%/L White blood cell count 18.6 x 10%/L 4.9-12.8 x 10%/L Platelet count 27 x 10%/L 215-450 x 10%/L 00 Blood film Dearrow_forward
- A 67 years old female patient. She presented to her GP last week, complaining of a very strong headache, followed by dizziness. The symptoms had resolved by the time she could see the GP, who was concerned enough to request a CT of her head and neck. Diabetes mellitus Type 2: Management: metformin 1000mg, daily enalapril 10 mg daily rosuvastatin 10mg, daily Atrial fibrillation (AF) Management: apixaban 2.5 mg, BD sotalol 40 mg, BD Cigarette smoking: 20 - 30 cigarettes/day, quit 5 years ago. She underwent a CT scan of the head and neck, but the results were normal. the patient was assessed as requiring changes to her hypertension & AF management and the following changes made: enalapril ceased the following medications commenced or changed; irbesartan/ hydrochlorothiazide 300/25, daily amlodipine 5mg, daily apixaban 5mg, BD This morning patient woke up at 0600 hours with a 5/10 headache. At 0700 hours she began to feel weak in her limbs, and her headache increased to…arrow_forwardThis 58-year-old nuclear power plant worker saw his family physician because of increasing fatigue and weakness. He also reported pain in his lower back and arms when he walks. Physical examination revealed that the man had pale mucous membranes and hepatosplenomegaly. The physician orders a complete blood count (CBC) and urinalysis (UA). A follow-up appointment is scheduled for the following week. Laboratory Data The CBC revealed that the patient had anemia. His leukocyte count and differential count were normal, except for a rouleaux (rolled coin) appearance of the RBCs. The UA was normal. The patient was called and requested to return to the laboratory for additional tests. The physician ordered an ESR, kidney screening profile, liver blood profile, and radiographic skeletal survey, with the following results: ESR—50 mm/hr Kidney profile—normal Liver profile—normal, except for increased globular protein Skeletal survey—bone lesions in various sites What follow-up laboratory tests…arrow_forwardWhat are the common laboratory tests for diagnosis of pernicious anemia? Please answer at your own words.arrow_forward
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