Given: Your cousin Sofia has not been feeling well lately. She felt hot and anxious all the time, and experienced raised heart rate (> 100 times/sec), palpitation, insomnia, and weight loss (>10 pounds). After multiple doctors’ visits, she was diagnosed with Graves’ disease. Please answer the following questions:Why did Sofia have the above symptoms?The doctors found the T3 and T4 levels in Sofia’s blood were much higher than normal standards, and her TSH level was zero. Please explain why?An endocrinologist prescribed a medicine called methimazole for Sofia. Methimazole blocks the iodination of tyrosyl residues and, therefore, inhibits the synthesis of T3 and T4 in thyroid gland. The doctor said it will take one or two months for the drug to lower Sofia’s hormone level. Please explain why it would take so long for Sofia to finally feel better.(Answer 1,2,3)

1. Sofia was diagnosed with graves disease which is an autoimmune disorder that causes…

Answered: Given: Your cousin Sofia has not been…

Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

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Given: Your cousin Sofia has not been feeling well lately. She felt hot and anxious all the time, and experienced raised heart rate (> 100 times/sec), palpitation, insomnia, and weight loss (>10 pounds). After multiple doctors’ visits, she was diagnosed with Graves’ disease. Please answer the following questions:

Why did Sofia have the above symptoms?
The doctors found the T3 and T4 levels in Sofia’s blood were much higher than normal standards, and her TSH level was zero. Please explain why?
An endocrinologist prescribed a medicine called methimazole for Sofia. Methimazole blocks the iodination of tyrosyl residues and, therefore, inhibits the synthesis of T3 and T4 in thyroid gland. The doctor said it will take one or two months for the drug to lower Sofia’s hormone level. Please explain why it would take so long for Sofia to finally feel better.

(Answer 1,2,3)

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