A 48-year-old woman of Mediterranean de- scent presents because of fatigue, arthralgias, discomfort in her right upper abdominal quad- rant, and polyuria. Laboratory tests are remark- able for elevated glucose level, elevated biliru- bin, low hemoglobin, elevated reticulocytes, and increased transferrin saturation. Cardiac testing shows moderate restrictive cardiomyop- athy. She frequently has required blood trans- fusions throughout her life. Which hereditary disorder does this patient most likely have?

A 35 year old woman of Chinese ethnic background (Guangdong province) presented with a near normal Haemoglobin level of 112 g/L. On performing a Full Blood Count (FBC) she was found to have an erythrocyte Mean Cell Volume (MCV) of 64.9fL and a Mean Cell Haemoglobin (MCH) value of 20.6 pg.A family study was performed on her father, mother and younger brother, including capillary electrophoresis. The following values were found:Father Mother Brother Patient Normal Range Age               74          69          32          35Hb (g/L)          98          107          113          112          133-167 (m)                                                       118-148 (f)MCV (fL)          69          89.4          62.7          64.9          80-100MCH (pg)          22.5          29.2          20.1          20.6          28-32HbA (%)          98.0          97.2          97.8          98.0          97-98HbA2 (%)          2.0          2.7          2.2          2.0          1.5-3RBC (x1012/L)…

A 2-and-a-half-year-old kid who weighed 11kg and had no previous/ known medical conditions was hospitalised for various bruises for one week owing to thrombocytopenia. Immune thrombocytopenic purpura was identified as the cause.    In light of bleeding manifestations and extremely severe thrombocytopenia with platelet level of 3 109/L, patient was suggested for two units of whole blood, derived platelet transfusion and began on intravenous immunoglobulin at a dose of 1 mg/kg. Due to the lack of blood group B platelets, the patient, who is B Rhesus D positive, got O RhD positive WB-derived platelets.    During the second unit of platelet transfusion, the kid started to experience, shortness of breath, chill, and rigor. the patient became worse with a fever of 38 C, an oxygen saturation of 80% in room air, hypotension (94/56 mmHg), tachycardia (156 beats/minute), and tachypnea (26 breaths/minute).    Blood film evidence of spherocytosis and tiny agglutinations helped to explain why the…

action of 145 R Oblique coronal reformat 85. A 53-year-old woman develops acute shortness of breath 5 days after undergoing a total knee arthroplasty. Her respirations are 20min. Physical examiraton shows no abromal breath sounds. Laboratory studies show a plasma d-dimer concentration of 600 ng/mL (N<500). A chest x-ray shows no abnormalities. A CT scan of the chest along with an obique coronal retoma are shown. Which of the following arteries, indicated by the arrows, is most likely affected by this patient's condition? A) Left upper lobar OB) Left lower lobar OC) Right upper lobar OD) Right lower lobar OE) Main pulmonary F) Left pulmonary MacBook Air 66000 BA