A 23.9061 g of Ethambutol hydrochloride was diluted with 100 mL of water and was analyzed in a 1.0 dm polarimeter tube. What is the specific rotation if the observed rotation using a D-line sodium lamp at a 589 visible wavelength and at 25°C is +1.53°.  Calculate for the specific rotation of the sample What is the monograph specification for the specific rotation of ethambutol? Disposition

Organic Chemistry
8th Edition
ISBN:9781305580350
Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Chapter3: Stereoisomerism And Chirality
Section3.7: Optical Activity—how Chirality Is Detected In The Laboratory
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  1. A 23.9061 g of Ethambutol hydrochloride was diluted with 100 mL of water and was analyzed in a 1.0 dm polarimeter tube. What is the specific rotation if the observed rotation using a D-line sodium lamp at a 589 visible wavelength and at 25°C is +1.53°. 
  • Calculate for the specific rotation of the sample
  • What is the monograph specification for the specific rotation of ethambutol?
  • Disposition
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