37. A 21-year-old man with lymphoma refractory to radiation therapy and chemotherapyundergoes a bone marrow transplantation. Five days later, his temperature is 37°C(98.6°F) and leukocyte count is 200/mm3. Filgrastim is administered. The number ofwhich of the following cells is most likely increased in this patient after this treatment?A) B lymphocytesB) BasophilsC) MacrophagesOD) NeutrophilsOE) T lymphocytes

Filgrastim is a medication that belongs to a class of drugs called colony-stimulating factors. It is…

Answered: A 21-year-old man with lymphoma…

Phlebotomy Essentials

6th Edition

ISBN:9781451194524

Author:Ruth McCall, Cathee M. Tankersley MT(ASCP)

Publisher:Ruth McCall, Cathee M. Tankersley MT(ASCP)

Chapter1: Phlebotomy: Past And Present And The Healthcare Setting

Section: Chapter Questions

Problem 1SRQ

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. A) What is the significance of producing monoclonal antibodies? B) What is the role of cell culture in production of monoclonal antibodies? C) Name and briefly explain the use of any 4 commercially available monoclonal antibodies.
(38) Following a rattle snake bite, a patient is injected with horse anti-rattlesnake venom serum. Ten days later he has general weakness, headaches, muscular and joint pains, and dark urine. Laboratory studies show proteinuria. Serum concentrations of immunoglobulins are within the reference range, but serum C3 and C4 concentrations are decreased. Which of the following is the most likely pathological process? (A) Anaphylactic Reaction (B) Delayed Hypersensitivity to horse protei (C) Formation of antigen-antibody complexes containing horse proteins and human immunoglobulin (D) Formsation of antigen-antibody complexes containing snake venom proteins and a horse antibody (E) Systemic reaction to snake venom
Immune system protects our body from illnesses. a) Complete the table below to show the differences between the cells of the immune system involved in humoral immune response and cell-mediated immune response. Description Humoral immune response Cell-mediated immune response Origin of cells Primary cells Site of cell maturation b) What is the effect of an antigen on B cells? c) Name the substance that is secreted by macrophages and leucocytes to trigger immune responsed) State the effect of the substance named in (c) in immune response.
Why are lymph nodes often inflamed or swollen when we get sick? a) Your body is producing more white blood cells to fight the infection, and the increase in cell numbers causes them to swell b) The foreign invader is accumulating in your lymph nodes causing them to swell. c) Your body is trying to tell you something is wrong and they swell as an alarm system.
(56) A 1 year old boy dies of staphylococcal pneumonia. He has had multiple skin infections since birth. Separation of the umbilical cord was delayed. A skin window test was performed and no leukocyte accumulated on the cover ship. The cytometric analysis showed that only 5% of the T lymphocytes reacted with a monoclonal antibody to leukocyte functional antigen-1 chain (CD 18) compared with reactivity of 62 % for a normal subject. Just prior to death, his leukocyte count was 75,000/mm3. Which of the following is the most likely diagnosis? (A) AIDS (B) Cogenital Asplenia (C)Leukocyte Adhesion Deficiency (D) Severe Combined Immunodeficiency Disease (E) X linked agammaglobulinemia
66) A 68-year old man has a 1-month history of hemoptysis and weakness. He has smoked 2 packs of cigarettes per day for 50 years. Eyelid ptosis is present bilaterally. Muscle testing shows increasing strength during several seconds of effort. An X-ray of the chest shows a mass on the left upper lobe of the lungs . Antibodies are most likely to cross-react between the mass and which of the following? (A) Muscle mitochondria (B) Myofilaments (C) Na+ - K+ pump (D) Synaptic Ca2+ channels (E) Thyroid-stimulating hormone receptors
Which of the following is the most likely future outcome for a thymocyte just entering the thymus? A) activation by a B-cell B) apoptosis C) differentiation into a Tc cell D) migration to a lymph node E) formation of a granuloma
Which WBCs turn into macrophages in tissues? Which other WBC is a voracious phagocyte?
CTLs use the following membrane-bound protein interactions to “kill” a target cell through apoptosis: Question 8 options: A) IL-2/IL-2 receptor B) CD4/MHC II C) TCR/MHC II D) Fas/FasL
13) Which of the following best describes the mechanism of an antiplatelet medication? A) Inhibition of platelet aggregation B) Blocking of sodium channels C) Inhibition of the inflammatory response D) Inhibition of factor X conversion
True/False: Neutrophils regulate the production of active cathelicidins (a class of antimicrobial peptides) by segregating the inactive propeptide from the processing enzyme that cleaves and activates it in two different types of cytoplasmic granules. These two types of granules are induced to fuse with phagosomes after ingestion of microbes, bringing the processing enzyme and the propeptide together.

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