_____ is the combination of a seat, elation, another modifications to the histones that allow for changes in DNA winding and unwinding a. Epigentics b. Histone code c. Heterochromatin d. Post translational modifications
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_____ is the combination of a seat, elation, another modifications to the histones that allow for changes in DNA winding and unwinding
a. Epigentics
b. Histone code
c. Heterochromatin
d. Post translational modifications
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Solved in 2 steps
- Loosening the chromatin structure occurs because of Select one: a. Lysine methylation b. Lysine acetylation c. Lysine phosphorylation d. Lysine sumoylationNew drugs are being developed that decrease DNA methylation and prevent the removal of acetyl groups from histone proteins. Explain how these drugs could affect gene expression to help kill tumor cells.Suppose a chemist develops a new drug that neutralizes the positive charges on the tails of histone proteins. What would be the most likely effect of this new drug on chromatin structure? Would this drug have any effect on gene expression? Explain your answers.
- Tightly coiled DNA is ________. a. known as hypermethylated b. translationally regulated c. transcriptionally inactiveEpigenetic changes in gene regulation are caused by _ _ _ _ _ _ _ a. missing nucleotides or chromosomes b. modifications to histones and the DNA, but not the nucleotide sequence itself c. mutations of the nucleotide sequence(b) (c) Point mutations in multiple tumor suppressor proteins have been linked to cancer. For example changes in the gene for adenomatous-polyposis-coli protein (APC gene) may result in colorectal cancer. Consider the following DNA sense strand. 3-TAC CGG TTG TGA AGC TGA ATC-5' Derive the mRNA molecule from the given DNA strand sequence above, paying attention to the polarity of the molecule. (i) (ii) (iii) (iv) Write down the polypeptide chain sequence arising from the mRNA molecule of the question above, using the table of the genetic code (Table Q1 overleaf) and indicate the C- and the N-terminus of the peptide chain. Point mutations of a cytosine (C) often lead to the dysfunction of the APC protein. Write down all possible polypeptide chains that can result from all possible DNA mutations of cytosines, disregarding a mutation in the MET/START and STOP codons. Specify which of the point mutations identified in (d) are redundant? For the given tRNA for Thrombin (Thr) write down all…
- Which of the following may produce more than one functional protein from an mRNA transcript?a. chromatin condensation b. transcriptional regulation c. epigeneticsd. alternative mRNA processingExplain the steps in Histone Modification in the process of Phosphorylation. Take note, important enzymes and chemicals are needed in your explanation.What factors are utilized by the cell in order to recognize the stop codon and disassemble the translation machinery? A. elongation factors B. release factors C. transcription factors D. initiation factors E. mRNA factors
- Complete the phrases with the correct word or words. The task is to match the lettered items with the correct numbered items. Appearing below is a list of lettered items. Following that is a list of numbered items. Each numbered item is followed by a drop-down. Select the letter in the drop down that best matches the numbered item with the lettered alternatives. a. methionine b. ribosome c. codon d. AUG e. UAC The mRNA moves out of the nucleus and attaches to a The first codon of an mRNA molecule is always As soon as the first codon is in place, a tRNA molecule arrives with the anti-codon The first tRNA to arrive always carries the amino acid called, The ribosome scoots along the mRNA to read the nextFor each statement below indicate whether it is true or false: A. Strand discrimination during the process of DNA repair is based on DNA methylation B. The genetic code has 64 amino acid-specifying codons C. Mutations in germline cells are more consequential to subsequent generations than mutations in somatic cells.Histones form more accessible chromatin because of Select one: a. Reduced electrostatic attraction between the histone and the negatively charged DNA backbone b. Increased electrostatic attraction between the histone and the negatively charged DNA backbone c. Reduced covalent bonding between the histone and the negatively charged DNA backbone d. Increased covalent bonding between the histone and the negatively charged DNA backbone