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log (10) -1 -2 -3 - 2 3 Slope = 1 Slope = 1 ----- -2 0 log po₂ Slope = 2.5 1 2 3 9.Shown below are the Hill plots of myoglobin (cyan) and an unknown 02 binding protein (magenta). (a) Does this unknown protein bind to 02 cooperatively? If so, is it a positive or negative cooperativity? (b) Does binding of the 1st 02 increase or decrease the affinity for the 2nd O2? (c)What is the minimal number of 02 binding sites that this unknown protein has? Why?

log (10) -1 -2 -3 - 2 3 Slope = 1 Slope = 1 ----- -2 0 log po₂ Slope = 2.5 1 2 3 9.Shown below are the Hill plots of myoglobin (cyan) and an unknown 02 binding protein (magenta). (a) Does this unknown protein bind to 02 cooperatively? If so, is it a positive or negative cooperativity? (b) Does binding of the 1st 02 increase or decrease the affinity for the 2nd O2? (c)What is the minimal number of 02 binding sites that this unknown protein has? Why?

Biochemistry
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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log (10) -1 -2 -3 - 2 3 Slope = 1 Slope = 1 ----- -2 0 log po₂ Slope = 2.5 1 2 3
Transcribed Image Text:log (10) -1 -2 -3 - 2 3 Slope = 1 Slope = 1 ----- -2 0 log po₂ Slope = 2.5 1 2 3
9.Shown below are the Hill plots of myoglobin (cyan) and an unknown 02 binding protein (magenta). (a) Does this unknown protein bind to 02 cooperatively? If so, is it a positive or negative cooperativity? (b) Does binding of the 1st 02 increase or decrease the affinity for the 2nd O2? (c)What is the minimal number of 02 binding sites that this unknown protein has? Why?
Transcribed Image Text:9.Shown below are the Hill plots of myoglobin (cyan) and an unknown 02 binding protein (magenta). (a) Does this unknown protein bind to 02 cooperatively? If so, is it a positive or negative cooperativity? (b) Does binding of the 1st 02 increase or decrease the affinity for the 2nd O2? (c)What is the minimal number of 02 binding sites that this unknown protein has? Why?
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