Q: 1. Which are the starting materials used to synthesize the given compound through reductive…
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Q: Write the mechanism for the following reactions: 1. the acid-catalyzed hydrolysis of an imine to a…
A: Any chemical bond's cleavage gets catalyzed by using any protic acid through "nucleophilic…
Q: 2) Propose two ways to synthesize the amine shown starting with an alkyl halide. (3
A: The reactions involving organic compound are known as organic reactions. Amines are organic…
Q: Rank the amines in each set in order of increasing basicity. H ot (b)bims n N (a) H. NH2 NH2 (c) H H…
A: ***Note: Since you have posted a question with multiple subparts, we will solve the first three…
Q: H,N N- -NH3 CI CHRYSOIDINE
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Q: Predict the product of the hydrolysis reaction below. Show any amine functional groups as neutral.…
A: The detailed solution of your question given below--
Q: What reaction involving amines is required to produce N-Propylcycloheptanamine? Propose a synthesis…
A: Since you have asked multiple questions, we will solve first question for you. Kindly post the…
Q: 18. Explain why at least two molar equivalents of an amine are usually needed to obtain a high yield…
A: In this reaction nh3 1st remove the leaving group because of this leaving group form salt with amine…
Q: 2) Predict the products formed when the following amides are treated with bromine and sodium…
A: Hoffman reaction
Q: Which amines cannot be prepared by a Gabriel synthesis? Explain your choices. NH2 NH2 NH2 а. b. C.…
A: Gabriel's phthalimide synthesis is used for the conversion of primary alkyl halide into primary…
Q: 9. How might you prepare the following amides from ethanoyl chloride? (a) N-ethylethanamide (b) N,…
A: The reaction for the preparation of the following compounds is as follows:
Q: 4. What is another more common name of the basic hydrolysis of an ester? (1 pt) 5. What is the…
A: Ans 4) Basic hydrolysis of an ester is also called Seponification . In this process ester (∆)…
Q: 7. The secondary amine and aldehyde below will react to form HN. a. An imine b. An enamine c. A…
A: The amine is nucleophile and the carbonyl carbon is the electrophile. So nucleophilic attack takes…
Q: 2) What amine can be used to produce the following imine from a ketone or aldehyde? NH2 А. В. `NH2…
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Q: 4. Propose a synthesis scheme for the amine shown below using the starting material indicated. No…
A: Here we have to prepare isopropyl amine from phthalimide by multistep reactions.
Q: Which of the following is FALSE about the reaction below? +0₂N NH₂ Select one: Oa. It is initiated…
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Q: Explain why a secondary amine forms a nitrosamine rather than a diazonium salt when it reacts with…
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Q: Show how Gabriel syntheses are used to prepare the following amines.(a) benzylamine
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Q: Which alkyl halide CANNOT be used effectively in a Gabriel synthesis of amines? Select one: a.…
A: Since you have asked multiple questions, we will solve the first question for you. If you want any…
Q: 1. Show the products of the reductive amination reactions below: a) Acetone + NH3, followed by…
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Q: 8. Propose two feasible syntheses of the amine shown below, starting from benzene and any needed In…
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Q: Which alkyl halide cannot be used effectively in a Gabriel synthesis of amines? Select one: a.…
A: The Gabriel synthesis is a chemical reaction that transforms primary alkyl halides into primary…
Q: 3. For the following amines, propose a stepwise synthesis for each compound. ? NH2 a) OH b)
A: Step 1 The given amines can be formed using the alkenes as one of the reactants and with the use of…
Q: show how you might prepare each of the following amines through reductive aminations…
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Q: Which amide would you treat with LIAIH4 to prepare the following compound? -CH2NHCH3 -CH2-Ċ-NH2…
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Q: 10) Which of the following will be the major product in the following reaction sequence? NO2 EN C 1)…
A: Primary amine - RNH2 , -NH2 group has only one carbon atom Secondary amine - R2NH, two carbon atom…
Q: 1(c) Provide the MAJOR products of the following reactions. CI, NaNH, A H, HO в Br, NaOH D CH,OH,…
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Q: The carboxylic acid shown below was used to prepare the amines A and B. Supply the missing reagents…
A: For synthesis of amine B , there should be degradation of carbon atom. Thus we have to recall…
Q: - How might the following amine be prepared using reductive amination reactions? Show all precursors…
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Q: 8. In the reaction below, why does the amine nitrogen (#1 in red) undergo protonation with H2SO4…
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Q: 5. The acyl group is a protecting group for amines which can be deprotected by treatment with sodium…
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Q: Show how you would prepare the following amide starting with bromocyclohexene and any other…
A: In this question, we will see the reagents for the preparing final product from the starting…
Q: Show how to synthesize the following amines from the indicated starting materials.(a)…
A: Given reactions, (a) N-cyclopentylaniline from aniline (b) N-ethylpyrrolidine from pyrrolidine
Q: - How would you prepare the following amines, using both Hofmann and Curtius rearrangements on a…
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Q: 1) How would you prepare phenylacetic acid (PHCH2CO2H) from benzyl bromide (PHCH2B1)?
A: Conversion of one compound to another desired compound is to be done by using specific reagent or…
Q: 5. show two different ways of preparing each of the following compounds via a reductive amination:…
A: In reductive amination reaction, carbonyl compound reacts with ammonia or amine to form an imine…
Q: Which of the following reductive amination reactions will yield a tertiary amine? *NH2 しiy H lime…
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Q: 人~ しi • NH
A: Amines with aldehyde or ketone forms imine, which on reduction with NaBH3CN forms amine.
Q: Show how you would prepare the following amide starting with bromocyclohexene and any other…
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Q: Show how Gabriel syntheses are used to prepare the following amines. ) hexan-1-amine
A: Gabriel synthesis is a chemical recation in which the primary alkyl halides is converted into…
Q: Show how to synthesize the following amines from the indicated starting materials.(a)…
A: Amines are the compounds that have NH2 group present in it. The lone pair of nitrogen can be donated…
Q: Show how Gabriel syntheses are used to prepare the following amines. g@aminobutyric acid
A: Gabriel syntheses: Alkyl halide is treated with phthalimide in the resence of base to give N-alkyl…
Q: Show how you can synthesize the following tertiary amine three different ways, each using a…
A: SOLUTION: Step 1: The different methods in which a tertiary amine can be synthesized using a…
Q: Which of these amine will react fastest in a reductive amination reaction?
A: Reductive amination is the successive conversion of primary amine into secondary amine and tertiary…
Q: a) What are the difficulties with the following reaction to synthesize an amine. + HBr Br + NH NH2…
A: Given reaction is :
Q: 3. For the following amines, propose a stepwise synthesis for each compound. ? NH2 a) ÓH ? b) ZI
A: Alkene converts to epoxide in presence of mcpba. Epoxide can be transformed into the target material…
Q: a. Write the mechanism for the following reactions:1. the acid-catalyzed hydrolysis of an imine to a…
A: To find: the acid-catalyzed hydrolysis of an imine to a carbonyl compound and a primary amine the…
Q: Which amines cannot be prepared by the Gabriel synthesis? Explain your choices
A: Gabriel synthesis: Gabriel synthesis is a chemical reaction that transforms an alkyl halide into a…
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- a) What are the difficulties with the following reaction to synthesize an amine. + HBr Br + NH3 NH2 b) Show a possible alternatives to this synthesis.1. Rank the following amines A-D in order of decreasing basicity, where 1 is the most basic. NO2 A B :ZIHow can you prepare the following amine using a reductive amination reaction?
- Show how to synthesize the following amines from the indicated starting materials below. Each of the final products may require several sequential steps. Draw the structure for each of the steps and show the reagents required. Starting material Final product e) 5-methylhexan-2-one 1-amino-2,5-dimethylhexan-2-ol f) 1-iodopropane tetrapropylammonium iodide g) 4-ethyl-3-methylhexan-1-ol 3-ethyl-2-methylpentan-1-amine2262 Sat Aor 6 1 Which one of the following compounds is the strongest acid? CNH2 -NH2 -CO2H OH CI- СОН CH CH C A B 2. Which one of the following amines will not produce an amide when mixed with an acid chloride? NH PHCH,NH2 PHNH2 Et,NH A C 3. What is the major product of the following sequence of reactions? CH3 1) NBS, hv (excess) C(OH)3 CHO CO2H CH2O 2) NaOH, H20 (excess) A В C 4. What is the major product of the following intramolecular aldol condensation reaction? E NaOH H20 (dehydration) A C 3. D. BShow how to synthesize the following amines from the indicated starting materials below. Each of the final products may require several sequential steps. Draw the structure for each of the steps and show the reagents required. Starting material Final product b) Benzene m-bromoaniline c) ethylbenzene p-ethylaniline + o-ethylaniline d) benzene p-bromoaniline + o-bromoaniline
- Which are viable ways to prepare the amine shown? || H NH + N ZI N NaBH3CN NaBH3CN A. Method I only B. Method II only C. Both methods are viable. D. Neither method is viable.1. What reaction involving amines is required to produce N-Propylcycloheptanamine? Propose a synthesis and mechanism2. Is the reaction below favorable or unfavorable? State your reasons.Norfloxacin is a is an antibiotic of the fluoroquinolone class used to treat urological infections. HN N A OH F There are two nitrogen atoms highlighted and labelled A and B. Match the highlighted nitrogen atoms to the appropriate classification of amines. 1. Primary amine v A 2. Secondary amine v B 3. Tertiary amine
- Amines and Amides 5. Base Hydrolysis a. Acetamide b. Benzamide Questions and Problems Q6 You have unknowns that are a carboxylic acid, an ester, and an amine. Describe how you would distinguish among them. రెండం we can acid an amine. Carlouxylicacid S have Dt ester s naue Sightiy ncutra DH and amine S Waue basic DH that 15jmore thon 7 Based on the OH of the Soutions distinquish Carooxy lic ester and an value Less than neutra 144b) Fill in the boxes to synthesize the following primary amines i) ii) iv) Br ΝΗ 1) 2) 3) aqueous workup 1) KOH 2) 3) H2N-NH2 NH3, HOAc, NaCNBH3 1) NaN3 2) PPh 3, H₂O NH₂ NH₂Show how to synthesize the following amines from the indicated starting materials byreductive amination. cyclohexylamine from cyclohexanone