579 to 582 (YIYV) in the PDGF-Beta receptor were eptor to give PDGF (YLIP) and EGF (YIYV) (Select all

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Which of the following would you expect to happen if amino acids 579 to 582 (YIYV) in the PDGF-Beta receptor were
exchanged with amino acids 992 to 995 (YLIP) from the EGF receptor to give PDGF (YLIP) and EGF (YIYV) (Select all
that apply)?
(A)
(B)
PDGF-B
receptor
Src
$8
&
P 579
P 581
YIYV
PI3KY
P 740 YMDM
NCK-a P 751 YVPM
P 771 YMAP
GAP
NCK-B
SHP2
PLC-y P
P 1009 YTAV
1021 YIIP
ala
845 YHAE
992 YLIP P
1045 YSSD
1068 YINQ
1086 YHNK
1148 YQQD
P
1173 YLRV
P
P
P
P
P
EGF
receptor
STAT3/5
PLC-y
Shc
Cbl
JAK2
Grb2
STAT3/5
Shc
SHP1
PTP1
Transcribed Image Text:Which of the following would you expect to happen if amino acids 579 to 582 (YIYV) in the PDGF-Beta receptor were exchanged with amino acids 992 to 995 (YLIP) from the EGF receptor to give PDGF (YLIP) and EGF (YIYV) (Select all that apply)? (A) (B) PDGF-B receptor Src $8 & P 579 P 581 YIYV PI3KY P 740 YMDM NCK-a P 751 YVPM P 771 YMAP GAP NCK-B SHP2 PLC-y P P 1009 YTAV 1021 YIIP ala 845 YHAE 992 YLIP P 1045 YSSD 1068 YINQ 1086 YHNK 1148 YQQD P 1173 YLRV P P P P P EGF receptor STAT3/5 PLC-y Shc Cbl JAK2 Grb2 STAT3/5 Shc SHP1 PTP1
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