5.5 Explain the effect of each type of inhibitor on the apparent kinetic parameters: Inhibitor binds only free enzyme Vmax O increases V does not change O decreases Km V increases O does not change O decreases Inhibitor binds only ES complex Vmax O increases O does not change V decreases Km O increases V does not change O decreases Inhibitor binds E and ES equally Vmax O increases O does not change V decreases Km O increases O does not change V decreases

Biochemistry
6th Edition
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Reginald H. Garrett, Charles M. Grisham
Chapter18: Glycolysis
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5.5 Explain the effect of each type of inhibitor on the apparent kinetic parameters:
Inhibitor binds only free enzyme
Vmax
O increases
V does not change
O decreases
Km
V increases
O does not change
O decreases
Inhibitor binds only ES complex
Vmax
O increases
O does not change
V decreases
Km
O increases
V does not change
O decreases
Inhibitor binds E and ES equally
Vmax
O increases
O does not change
V decreases
Km
O increases
O does not change
V decreases
Transcribed Image Text:5.5 Explain the effect of each type of inhibitor on the apparent kinetic parameters: Inhibitor binds only free enzyme Vmax O increases V does not change O decreases Km V increases O does not change O decreases Inhibitor binds only ES complex Vmax O increases O does not change V decreases Km O increases V does not change O decreases Inhibitor binds E and ES equally Vmax O increases O does not change V decreases Km O increases O does not change V decreases
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