Biochemistry
Biochemistry
9th Edition
ISBN: 9781319114671
Author: Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher: W. H. Freeman
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**5.5 Explain the effect of each type of inhibitor on the apparent kinetic parameters:**

**Inhibitor binds only free enzyme**

**Vmax:**

- [ ] increases
- [x] does not change
- [ ] decreases

**Km:**

- [x] increases
- [ ] does not change
- [ ] decreases

---

**Inhibitor binds only ES complex**

**Vmax:**

- [ ] increases
- [ ] does not change
- [x] decreases

**Km:**

- [ ] increases
- [ ] does not change
- [x] decreases

---

**Inhibitor binds E and ES equally**

**Vmax:**

- [ ] increases
- [ ] does not change
- [x] decreases

**Km:**

- [ ] increases
- [x] does not change
- [ ] decreases
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Transcribed Image Text:**5.5 Explain the effect of each type of inhibitor on the apparent kinetic parameters:** **Inhibitor binds only free enzyme** **Vmax:** - [ ] increases - [x] does not change - [ ] decreases **Km:** - [x] increases - [ ] does not change - [ ] decreases --- **Inhibitor binds only ES complex** **Vmax:** - [ ] increases - [ ] does not change - [x] decreases **Km:** - [ ] increases - [ ] does not change - [x] decreases --- **Inhibitor binds E and ES equally** **Vmax:** - [ ] increases - [ ] does not change - [x] decreases **Km:** - [ ] increases - [x] does not change - [ ] decreases
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