5.5 Explain the effect of each type of inhibitor on the apparent kinetic parameters:
5.5 Explain the effect of each type of inhibitor on the apparent kinetic parameters:
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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Please explain your reasoning for every answer
![**5.5 Explain the effect of each type of inhibitor on the apparent kinetic parameters:**
**Inhibitor binds only free enzyme**
**Vmax:**
- [ ] increases
- [x] does not change
- [ ] decreases
**Km:**
- [x] increases
- [ ] does not change
- [ ] decreases
---
**Inhibitor binds only ES complex**
**Vmax:**
- [ ] increases
- [ ] does not change
- [x] decreases
**Km:**
- [ ] increases
- [ ] does not change
- [x] decreases
---
**Inhibitor binds E and ES equally**
**Vmax:**
- [ ] increases
- [ ] does not change
- [x] decreases
**Km:**
- [ ] increases
- [x] does not change
- [ ] decreases](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2Ff8bc65dc-daaa-436a-8312-64a8b045c818%2Fe5186597-4b33-4c0e-9e08-01eabda6d5ba%2Fnx42rck_processed.png&w=3840&q=75)
Transcribed Image Text:**5.5 Explain the effect of each type of inhibitor on the apparent kinetic parameters:**
**Inhibitor binds only free enzyme**
**Vmax:**
- [ ] increases
- [x] does not change
- [ ] decreases
**Km:**
- [x] increases
- [ ] does not change
- [ ] decreases
---
**Inhibitor binds only ES complex**
**Vmax:**
- [ ] increases
- [ ] does not change
- [x] decreases
**Km:**
- [ ] increases
- [ ] does not change
- [x] decreases
---
**Inhibitor binds E and ES equally**
**Vmax:**
- [ ] increases
- [ ] does not change
- [x] decreases
**Km:**
- [ ] increases
- [x] does not change
- [ ] decreases
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