5. On this replication fork, draw in all of the enzymes and proteins required for DNA replication (DNA Polymerase, helicase, topoisomerase, ligase, primase, and exonuclease). Also draw in and label the primer and new DNA. Indicate which is the leading and lagging strand Label all 5' and 3' ends.

13. Draw deoxyribonucleosides in the conformation they would appear in Z-DNA and B-DNA.

1. Okazaki fragments are small pieces of DNA synthesized discontinuously on the lagging strand of DNA during replication (true or false) 2. during replication DNA polymerase synthesize DNA in the 5 or 3 direction (true or false)

Pls help ASAP

1. Name all the proteins that are in the DNA replication fork in E. Coli, and describe the functions of these proteins. Explain how two DNA strands are replicated at the same time by one replication fork.

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4.) During DNA replication, the two strands of DNA are pried apart and then serve as templates for synthesis of new strands. However, there are some big differences in how the two strands are copied. Why is this so? Please describe in 4-5 sentences of your own words how replication proceeds on the two strands. 5.) During meiosis, when crossing-over occurs between two homologous chromosomes, it does not happen at a single point, but rather two points with a stretch of DNA in between. What are the two junction points called? b. What is the region between the two points called and what is different about this region compared to how double-stranded DNA usually is? c. If the region described in b.) is located within a gene and the two homologues have different alleles of this gene, what might happen that is a direct violation of Mendel's first law? (Describe the process with 2-3 sentences of detail.) a.

7. Which of the following phosphates in a single-stranded DNA molecule is covalently attached to a carbon (in the deoxyribose sugar), but that phosphate is not part of a phosphodiester bond? the phosphate attached to the 5’-carbon on the first deoxyribose sugar of this single DNA strand the phosphate attached to the 5’-carbon on the last deoxyribose sugar of this single DNA strand the phosphate attached to the 3’-carbon on the first deoxyribose sugar of this single DNA strand the phosphate attached to the 3’-carbon on the last deoxyribose sugar of this single DNA strand all of the above

5. Draw the major components of the DNA Pol III replication complex in the context of a replication fork. Be sure to illustrate and label the leading and lagging strands, RNA primers, Okazaki fragments, the polymerase core, the beta-clamp subunits, and the clamp loader complex, and show how the lagging strand is threaded through the replication complex.

1. Drag each of the following events according to their ability to create spontaneous mutations vs. induced mutations.     Nucleotide misincorporation during DNA replication Tautomer shifts of DNA bases Ultraviolet light Alkylating agents 5-Bromouracil     Spontaneous Mutation   Induced Mutation   2.  After ONE round of DNA replication in Meselson and Stahl's classic experiment, ________.   both the conservative and the semiconservative models were still possibilities the conservative model was conclusively proven to be incorrect the semiconservative model was conclusively proven to be the correct one all three models of replication were still possibilities the dispersive model was conclusively proven to be incorrect