3. Write the mechanism (including resonance forms) for the electrophilic aromatic substitution reaction shown below. CH3. + Br2, AlBr3 CH37 Br

A Quiz: Final Exam Part 1 s.edu/courses/450650/quizzes/3419517/take Question 16 Thionyl choride, SOCI2, is a reagent commonly used to convert the -OH group of an alcohol to a better leaving group. What is the formal charge on S in this molecule? ts :0; O +2 O+1 O-1 O-2 88 F3 F4

Substitution Reactions Predicting the product of a nucleophilic substitution reaction Draw the organic product you would expect to isolate from the nucleophilic substitution reaction between the molecules shown. Note: You do not need to draw any of the side products of the reaction, only the substitution product. HO + + Br xx X S C Click and drag to start drawing a structure.

Following is a balanced equation for the allylic bromination of propene. CH2==CHCH3 + Br2 h CH2==CHCH2Br + HBr (a) Calculate the heat of reaction, H 0, for this conversion. (b) Propose a pair of chain propagation steps and show that they add up to the observed stoichiometry. (c) Calculate the H 0 for each chain propagation step and show that they add up to the observed H 0 for the overall reaction.

Can you explain it? Provide examples with the various steps and explanations. How halogens affect the boiling/melting point? Does number of halogens affect it? For example, Ch3-Ch3 vs Ch3-Br vs Br-Ch3-Br

First Writedown which reaction it is? SN1, SN2, E1? Write a stepwise mechanism for the following reactions showing ALL intermediates. Use curved arrows to symbolize the flow of electrons to show how each of the intermediates and product are formed. Show all necessary lone pairs and formal charges.

The reaction shown proceeds via a single transition state with a trigonal bipyramidal geometry. C1 C2 Br: + H3C 0: Two curved arrows are required to indicate all of the bond-making and bond-breaking processes in this reaction. Where should one of the arrows be drawn, if CH3O is the nucleophile? from a Br LP to the O atom from C1 to the O atom from C2 to the O atom from the C-O bond to Br from an O LP to C1 from an O LP to C2

2. Provide an arrow pushing mechanism for the following reaction. Show all intermediate structures and formal charges. You do not need to show resonance structures

4. Propose a structure(s) for the product(s) of the following reactions. НО HNO3, H2SO4, Br NO2 H,SO4

[Review Topics] [References] Br H3C CH3 H3C H3C 1. Aqueous ethanol + HO +] H. CH3 H. CH3 BH3 O-BH3 f=Sn1 Nucleophilic substitution g = Sn2 Nucleophilic substitution a = Proton transfer d = El Elimination b Lewis acid/base e = E2 Elimination c = Electrophilic addition The rections above involve synthesis or reactions of alcohols and ethers. Identify the mechanism by which they proceed from among the mechanisms listed. Use the letters a - gf answers. 2.