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- 9. Be able to recognize examples of cellular responses that can be the outcome of a signal transduction mechanism.4. Which of the following statements are correct? A. Signalling molecules that are lipid-soluble bind to extracellular receptors B. Transcription factors can regulate the expression of genes C. A signalling molecule always binds to the same receptor, regardless of the cell it targets D. A scaffolding protein binds to multiple relay proteins, but not simultaneously E. Phosphatases can phosphorylate protein kinases26.With regard to cell signalling, which of the following do not represent exogenous signals? A. Neurotransmitters B. Invading microorganisms C. Light D. Odours E. All of the above statements are correct 27.Which of the following statements correctly describe distinct aspects of microtubule dynamic instability? A. αβ-tubulin dimers must contain GTP bound to both subunits to be added to a microtubule B. Terminal β-subunits have essentially negligible rates of GTP hydrolysis C. The addition of a new αβ-tubulin dimer to a growing microtubule results in GTP hydrolysis within the formerly terminal β-tubulin subunit D. The end of each microtubule has a cap of GTP-bound β-subunits, with the central region of the microtubule primarily consisting of GDP-bound β-subunits E. All of the above statements are true 28.All of the following statements regarding myosin are true, with the exception of: A. Myosin is a multimeric protein made up of heavy and light chains B.…
- 2. In the images above, use the scale bar to deduce what are you most likely to be looking at. What do you think is being shown in the figure? A. An image of many cells in a tissue. B. A sub-cellular image. C. An image of a whole cell. The location of phosphatidylserine (PS) was visualized in the figure above by a protein called annexin that specifically recognizes and binds to PS. Annexin was injected into a blood vessel in the live embryo at either day E13 (left) or E14 (right). The live embryo was cultured for 30 min before fixing and staining. Annexin can leak out of embryonic blood vessels by leaking between the immature cells. Annexin is labeled in brown. Ignore the arrows..3.Cell surface receptors used in cell signalling are usually proteins that extend from one sid of the membrane to the other side of the membrane. What is the role of the extracellular part of the protein? A. binding the signalling molecule B. functioning as an enzyme C. increasing the solubility of the receptor D. transmitting the signal from the target cell1.create a Graphical Abstract to summarise the role of ALP in cancer?With image
- 6. An individual contracts an infection and this results in the production of soluble proteins that act as signalling molecules between cells. Outline and differentiate the various biological activities of these molecules.ge You have found a plant-derived compound that interferes with microtubule assembly by binding to and blocking free cytosolic tubulin. This compound might help treat by interfering with the Select one: a. Cancer, p53 b. Cancer, cyclin c. Parkinsons, mitotic spindle d. Cancer, mitotic spindle e. Parkinsons, cyclin Next page3. Equal numbers of fibroblasts and endothelial cells are present initially in a culture. a. If the endothelial cells double every 40 hours and the fibroblasts double every 20 hours, draw a graph showing the percentage of cells in the culture that are fibroblasts as a function of time (you can use excel). b. Come up with an equation to determine the time at which 90% of the cells will be fibroblasts and solve for time. Explain how you came up with your equation.
- 13.Paracrine regulation of homeostasis means a. a cell is altering its own genetic response (transcription) in order to facilitate a homeostatic response b. there is a whole-body response that brings about homeostatic balance c. a cell targets and regulates a nearby cell d. a cell is regulating its own homeostatic response 14.Which of the following is/are symptoms of cystic fibrosis? A. shortness of breath B. persistent cough C. seizures D. poor growth or weight gain E. memory loss F. salty skin G. wheezing H. frequent lung infections I. greasy stools 15. Given an intracellular Na+ concentration of 10 mM and an extracellular Na+ concentration of 142mM; when the Em = - 70mV, the chemical gradient draws Na+ ___________ the cell, the electrical gradient draws Na+ __________ the cell, and the net (overall) forces draw Na+ _______________ the cell.…3. There were a variety of different types of control methods used into today’s lab (i.e. hot sauce, mouth wash, alcohol, etc.). Which one(s) do you think will work effectively and why? Think about what part of the cell would be affected by the control and explain.10. The diagrams below represent two cells, X and Y. * B C C Cell X Cell Y Identify one process that is carried out in cell Y in the diagram that is not carried out in cell X. Your answer L.