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- 4. Devise a synthesis for the following compound Booksa.) b.) LOCH 3 CHO Determine and draw the product of the following reactions. HNO3 / H₂SO4 HNO3 / H₂SO4 c.) ОНС d.) CH3 OCH3 CH3 OCH3 HNO3 / H₂SO4 HNO3/H₂SO44. Design a synthetic scheme using any reagents and reactions that have been discussed in CHEM2402. Only reactions and reagents from CHEM2402 will be considered. a) i) ii) iii) iv) Br Br Br Br the ماں S. OCH3
- 1K.) Electrophilic aromatic substitution (EAS) nitration of pyridine (shown below) results in what type of major product? HNO3, H₂SO4 NO₂ b.) NO₂ NO₂ c.) NO₂ NO₂ ? cannot be determined d.)A. B. C. D. E. Br Br H H OH Which of these synthetic2. The following drugs are synthesised using the methods in this chapter and previous chapters. Derive a synthesis for each, starting with any compounds containing no more than six carbons atoms. A. Phenacetin, used with aspirin and caffeine in pain-relief medications B. Methamphetamine, once considered a safe diet pill, but now known to be addictive and destructive to brain tissue. C. Dopamine, one of the neurotransmitters in the brain. Parkinson's disease is thought to result from a dopamine deficiency.
- Select the keyword or phrase that will best complete each sentence. Key terms: backside carbocation elimination frontside hyperconjugation inversion maintenance nucleophile product racemization stronger substitution weaker Alkyl halides undergo A orbital. reactions with Brønsted-Lowry bases. is a sp² hybridized and trigonal planar and contains a vacant p All SN2 reactions proceed with in attack of the nucleophile, resulting of configuration at a stereognic center. Spreading out charge by the overlap of an empty p orbital with an adjacent o bond is called Equilibrium favors the products of nucleophilic substitution when the leaving group is a base than the nucleophile. According the to Hammond postulate, the stability of the determines the rate of its formation. The formation of equal amounts of two enantiomeric products from a single starting material is called A is an electron-rich compound, which donates a pair of electrons to an electron deficient compound, forming a covalent bond.…Propose an efficient synthesis of the following molecules.Determine reagents C and D from the reaction scheme below.