3- Insulin-like growth factor 1 (IGF-1) is a hormone that plays an important role in childhc growth and may be associated with several types of cancer. In some studies, it is measured in serum, and in other studies it is measured in plasma. Blood plasma is prepared by spinning a tube of fresh blood containing an anti-coagulant in a centrifuge until the blood cells fall to the bottom. The blood plasma is then poured or drawn off. Blood serum is blood plasma without clotting factors (i.e., whole blood minus both the cells and the clotting factors). In a multi-center study, IGF-1 was measured in some centers with serum and in other centers with plasma. The following results were obtained: TABLE 8.33 Comparison of IGF-11evels measured in serum vs. plasma IGF-1 (ng/mL) mean sd serum 140 149.1 42.3 plasma 404 136.6 49.0 Assuming that the distribution of IGF-1 is approximately normal, and equality of the variances, nat test can be used to compare the mean IGF-1 obtained from the two sources? Perform the test in Problem (i) and write your interpretation.

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entire week?
3- Insulin-like growth factor 1 (IGF-1) is a hormone that plays an important role in childhood
growth and may be associated with several types of cancer. In some studies, it is
measured in serum, and in other studies it is measured in plasma. Blood plasma is
prepared by spinning a tube of fresh blood containing an anti-coagulant in a centrifuge
until the blood cells fall to the bottom. The blood plasma is then poured or drawn off.
Blood serum is blood plasma without clotting factors (i.e., whole blood minus both the
cells and the clotting factors). In a multi-center study, IGF-1 was measured in some
centers with serum and in other centers with plasma. The following results were
obtained:
TABLE 8.33 Comparison of IGF-11evels measured
in serum vs. plasma
IGF-1 (ng/mL)
mean
sd
serum
140
149.1
42.3
plasma
404
136.6
49.0
) Assuming that the distribution of IGF-1 is approximately normal, and equality of the variances,
what test can be used to compare the mean IGF-1 obtained from the two sources?
ii) Perform the test in Problem (i) and write your interpretation.
4- A drug company is developing a new pregnancy-test kit for use on an outpatient basis.
The company uses the pregnancy test on 100 women who are known to be pregnant, for
whom 95 test results are positive. The company uses the pregnancy test on 100 other
rar:Jalsil vaill 2n who are known to not be pregnant, of whom 99 test negative.
Transcribed Image Text:entire week? 3- Insulin-like growth factor 1 (IGF-1) is a hormone that plays an important role in childhood growth and may be associated with several types of cancer. In some studies, it is measured in serum, and in other studies it is measured in plasma. Blood plasma is prepared by spinning a tube of fresh blood containing an anti-coagulant in a centrifuge until the blood cells fall to the bottom. The blood plasma is then poured or drawn off. Blood serum is blood plasma without clotting factors (i.e., whole blood minus both the cells and the clotting factors). In a multi-center study, IGF-1 was measured in some centers with serum and in other centers with plasma. The following results were obtained: TABLE 8.33 Comparison of IGF-11evels measured in serum vs. plasma IGF-1 (ng/mL) mean sd serum 140 149.1 42.3 plasma 404 136.6 49.0 ) Assuming that the distribution of IGF-1 is approximately normal, and equality of the variances, what test can be used to compare the mean IGF-1 obtained from the two sources? ii) Perform the test in Problem (i) and write your interpretation. 4- A drug company is developing a new pregnancy-test kit for use on an outpatient basis. The company uses the pregnancy test on 100 women who are known to be pregnant, for whom 95 test results are positive. The company uses the pregnancy test on 100 other rar:Jalsil vaill 2n who are known to not be pregnant, of whom 99 test negative.
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