24. People with an autoimmune disease like lupus produce antibodies that react to their own tissues. Research has shown that lupus-prone strains of mice have B cells with redudd expression levels of the receptor gene SYRIIB, suggesting that low expression of this gene might contribute to the autoimmune reaction. To test this, McGaha et al. (2005) experimentally enhanced expression of the FcyRIIB gene in bone marrow taken from a lupus-prone mouse strain and transplanted it back into irradiated mice of the same strain. Other mice of the same strain were subjected to the same procedures but received bone marrow that was not enhanced for FcyRIIB expression (i.e., the sham treatment). Mice in a third group were left untreated. Auto- immune reactivity was measured six months later. The following is a frequency table indi- cating the highest dilution of blood serum, in a fixed series of dilutions, at which reactivity could be detected (a high dilution reflects a high autoimmune reactivity).
24. People with an autoimmune disease like lupus produce antibodies that react to their own tissues. Research has shown that lupus-prone strains of mice have B cells with redudd expression levels of the receptor gene SYRIIB, suggesting that low expression of this gene might contribute to the autoimmune reaction. To test this, McGaha et al. (2005) experimentally enhanced expression of the FcyRIIB gene in bone marrow taken from a lupus-prone mouse strain and transplanted it back into irradiated mice of the same strain. Other mice of the same strain were subjected to the same procedures but received bone marrow that was not enhanced for FcyRIIB expression (i.e., the sham treatment). Mice in a third group were left untreated. Auto- immune reactivity was measured six months later. The following is a frequency table indi- cating the highest dilution of blood serum, in a fixed series of dilutions, at which reactivity could be detected (a high dilution reflects a high autoimmune reactivity).
MATLAB: An Introduction with Applications
6th Edition
ISBN:9781119256830
Author:Amos Gilat
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Chapter1: Starting With Matlab
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