2. Show the best method for preparing the following ether via the Williamson ether synthesis. Provide the step by step mechanism for the reactions. -OCH3
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- 1 Provide step by step analysis of each reagent and final product clearly indicatedUsing your reaction roadmap as a guide, show how to convert cyclohexane into hexanedial. Show all reagents and all molecules synthesized along the way.The first widely used herbicide for the control of weeds was 2,4-dichlorophenoxyacetic acid (2,4-D). Show how this compound might be synthesized from phenol and chloro-acetic acid by way of the given chlorinated phenol intermediate.
- 1. Provide stepwise synthesis including reagents and intermediates for the following syntheses. OH COOHH₂C CH3 Show how the compound can be synthesized from benzene and alkyl chlorides.provide a 5-step synthesis to arrive at the final structure. Provide intermediate steps and show arrow pushing mechanism. Please use the following reagents: 1. Mg, Et2O 2. CO2 3. H3O+ 4. SOCl2 5. 2 eq of HN(Et)2
- Complete the reaction schemes below providing the reagents required to achieve thetransformation. More than one step may be necessary for each scheme.The structure shown below is of Pitolisant (Waxix®), is a drug to treat narcolepsy. CI Pitolisant – Waxix® Below, see the synthesis of the compound. What are the reactions used? OMs OH OH CI CI O Two Williamson ether synthesis reactions. O Aminal formation followed by an ether interchange reaction. O An SN2 reaction followed by a Williamson synthesis.Provide a structure for the major products of the reactions and include the steps for each reaction.
- a) There are two possible pairs of carbonyl compounds and ylides to prepare the following alkene via Wittig reactions. H CH3 i. Propose both pairs of the starting reactants. ii. The above alkene can be converted to an aldehyde and a ketone. Provide a suitable reagent and reaction condition for the conversion.H₂Cr2O7 k. OH 4. Propose a reasonable synthesis of the following ether via Williamson etherification reaction8. Provide the reagents necessary to prepare the following compound using a Williamson ether synthesis.