2. Predict the products. (Hint: for the 2rd one, remember the driving force for a Claisen reaction, and that all the steps are reversible.) a) 1 equiv LDA in H b) O c) Mel a) NaOEt i b) H3O+ Et

A. Please provide the products of each reaction. H₂N CI CI OH F NaOCI CH3CN / Acetic Acid

Oraw a stepwise mechanism for the following reaction: Br CH3CH2OH Part 1 out of 3 HBr Br Br CH3CH,Br finish structure ... draw structure CH;Br

4. Regioselectivity Draw the major product formed for each reaction. Assume the reactions are irreversible. Include stereochemistry when products contain stereocenter(s). (a) Draw only the substitution product. Both elimination and substitution occur here. Hac Br CH₂OH (c) (b) CH3 CH3 Br H NaOCH3 80 °C 1 equiv CH3Li then

Draw the products of each reaction.

Review the SN1 reaction below: CI OCH 3 CH3OH + + CH3OH2 + Now consider the energy diagram for the above reaction. Energy Reaction Coordinate C E B D Draw the structure for intermediate(s) at D in the provided box below. D

3 4 points NaCN CH3CN Br Predict the product of the reaction shown above. , SN2 CN , E2 CN , SN1 No reaction occurs.

reaction by filling in any Starting materials, reagents or products as needed.

Draw the major product formed for each reaction. Assume the reactions are irreversible. Include stereochemistry when products contain stereocenter(s). (a) Draw only the substitution product. Both elimination and substitution occur here. H³C" Br CH3OH

Draw the product formed from cyclohex-2-enone in each of three reactions. Reaction 1 Reaction 2 Reaction 1 1. NaCN 1. (CH3)2CuLi Reaction 2 product product 2. H3O*, H20 2. CH3CH21 A 1. EtO,CCH,CO¿Et NaOEt, HOET 2. Hао", Н-0, д Reaction 3 Reaction 3 product