2. One of the purposes of an investigation by Porcellini et al. was to investigate the effect on CD4 T cell count of administration of intermittent interleukin (IL-2) in addition to highly active antiretroviral therapy (HAART). The following table shows the CD4 I cell count at baseline and then again after 12 months of HAART therapy with IL-2. Do the data show, at the 0.05 level, a significant change in CD4 T cell count?
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One of the purposes of an investigation by Porcellini et al. was to investigate
the effect on CD4 T cell count of administration of intermittent interleukin (IL-2) in addition to highly active antiretroviral therapy (HAART). The following table shows the CD4 T cell count at baseline and then again after 12 months of HAART therapy with IL-2.
Do the data show, at the 0.05 level, a significant change in CD4 T cell count?
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- Anemia (low healthy blood cells or hemoglobin) has an important role in exercise performance. However, the direct link between rapid changes of hemoglobin and exercise performance is still unknown. A study investigated 18 patients with a blood disorder (beta-thalassemia). Participants in the study performed an exercise test before and the day after receiving a blood transfusion. Data are given in the table. HB = Hemoglobin RER = Respiratory exchange ID Change in HB Obese RER > 1.1 ratio No No 1 -1.4 No -1.5 No Yes No Yes 3 -2 No 4 -2.1 No -1.9 Yes Yes No -1.6 -1.8 -0.8 6 7 No Yes No Yes 8 9. -1 No No -1.2 No Yes 10 11 No No -0.8 -1.5 12 Yes No No Yes 13 14 -1.4 -2.6 -1.7 No No Yes Yes 15 Yes No Yes Yes 16 -2.6 No 17 18 -2.7 -1.5 NoA medical student at a community college in city Q wants to study the factors affecting the systolic blood pressure of a person (Y) Generally, the systolic blood pressure depends on the BMI of a person (B) and the age of the person A. She wants to test whether or not the BMI has a significant effect on the systolic blood pressure, keeping the age of the person constant. For her study, she collects a random sample of 125 patients from the city and estimates the following regression function: Y= 15.50 + 0..90B+1.15A. (0.55) (0 40) The test statistic of the study the student wants to conduct (Ho: B, = 0 vs. H, B, #0), keeping other variables constant is. (Round your answer to two decimal places.) At the 5% significance level, the student will ▼ the null hypothesis. Keeping BMIl constant, she now wants to test whether the age of a person (A) has no significant effect or a positive effect on the person's systolic blood pressure. So, the test statistic associated with the one-sided test the…Captopril is a drug designed to lower systolic blood pressure. When subjects were treated with this drug, their systolic blood pressure readings (in mm Hg) were measured before and after the drug was taken. Results are given in the accompanying table (based on data from "Essential Hypertension: Effect of an Oral Inhibitor of Angiotensin-Converting Enzyme," by MacGregor et al., British Medical Journal, Vol. 2). Using a 0.01 significance level, is there sufficient evidence to support the claim that captopril has an effect on systolic blood pressure?
- 4. Captopril is a drug designed to lower systolic blood pressure. When subjects were treated with this drug, their systolic blood pressure readings (in mm Hg) were measured before and after the drug was taken. Results are given in the accompanying table (based on data from “Essential Hypertension: Effect of an Oral Inhibitor of Angiotensin-Converting Enzyme”, by MacGregor et al., BMJ, Vol. 2). Using a 0.01 significance level, is there sufficient evidence to support the claim that captopril has an effect on systolic blood pressure? Explain why statistical methods from Z-interval, Z-test, T-interval or T-test –cannot be used for this problem. Then, use the sign test to conduct the required test in R studio. Please show your work.The data in the attached image represents blood pressure based on a new trial medication used in an experiment involving a total of 50 male and female subjects. There were two levels of treatment: 0 = placebo and 1 = treatment group. Family History Blood Pressure = Fam-Hist-BP; from the paternal side = PS; from the maternal side = MS; from both sides = BS; none on both sides or not known = N.; Blood pressure before the experiment = BP-Before-Exp; Blood pressure after the experiment = BP-After-Exp. Task: Find the mean and standard deviation for the family history group, the before treatment group, and the after treatment group.Captopril is a drug designed to lower systolic blood pressure. When subjects were treated with this drug, their systolic blood pressure readings (in mm Hg) were measured before and after the drug was taken. Results are given in the accompanying table (based on data from “Essential Hypertension: Effect of an Oral Inhibitor of Angiotensin-Converting Enzyme”, by MacGregor et al., BMJ, Vol. 2). Using a 0.01 significance level, is there sufficient evidence to support the claim that captopril has an effect on systolic blood pressure? i) Use the Wilcoxon signed-ranks test to conduct the required test without using "wilcox.test" function in R. Please state the hypothesis, provide the p-value, and the conclusion in the context of the problem. ii) Use the Wilcoxon signed-ranks test to conduct the required test using "wilcox.test" function in R. Please present a screenshot of the R output of your call to the function wilcox.test. iii) Would you recommend the Wilcoxon signed-ranks test over the…
- The data in the attached image represents blood pressure based on a new trial medication used in an experiment involving a total of 50 male and female subjects. There were two levels of treatment: 0 = placebo and 1 = treatment group. Family History Blood Pressure = Fam-Hist-BP; from the paternal side = PS; from the maternal side = MS; from both sides = BS; none on both sides or not known = N.; Blood pressure before the experiment = BP-Before-Exp; Blood pressure after the experiment = BP-After-Exp. Task: Construct a side-by-side boxplot to compare the variables BP-Before-Exp and BP-After-Exp.The data in the attached image represents blood pressure based on a new trial medication used in an experiment involving a total of 50 male and female subjects. There were two levels of treatment: 0 = placebo and 1 = treatment group. Family History Blood Pressure = Fam-Hist-BP; from the paternal side = PS; from the maternal side = MS; from both sides = BS; none on both sides or not known = N.; Blood pressure before the experiment = BP-Before-Exp; Blood pressure after the experiment = BP-After-Exp. Task: Construct a scatterplot to display the relationship and find the correlation between age and BP-Before Exp.The data in the attached image represents blood pressure based on a new trial medication used in an experiment involving a total of 50 male and female subjects. There were two levels of treatment: 0 = placebo and 1 = treatment group. Family History Blood Pressure = Fam-Hist-BP; from the paternal side = PS; from the maternal side = MS; from both sides = BS; none on both sides or not known = N.; Blood pressure before the experiment = BP-Before-Exp; Blood pressure after the experiment = BP-After-Exp. Task: Construct a histogram to represent the family BP history, the subjects' BP before treatment and the subjects' BP after treatment.
- The data in the attached image represents blood pressure based on a new trial medication used in an experiment involving a total of 50 male and female subjects. There were two levels of treatment: 0 = placebo and 1 = treatment group. Family History Blood Pressure = Fam-Hist-BP; from the paternal side = PS; from the maternal side = MS; from both sides = BS; none on both sides or not known = N.; Blood pressure before the experiment = BP-Before-Exp; Blood pressure after the experiment = BP-After-Exp. Task: Construct a scatterplot to display the relationship and find the correlation between BP-Before-Exp and BP-After-Exp.The data in the attached image represents blood pressure based on a new trial medication used in an experiment involving a total of 50 male and female subjects. There were two levels of treatment: 0 = placebo and 1 = treatment group. Family History Blood Pressure = Fam-Hist-BP; from the paternal side = PS; from the maternal side = MS; from both sides = BS; none on both sides or not known = N.; Blood pressure before the experiment = BP-Before-Exp; Blood pressure after the experiment = BP-After-Exp. Task: Generate at least two different cross tabulations.A researcher hypothesizes that the lowering in cholesterol associated with weight loss is really due to exercise. To test this, the researcher carefully controls for exercise while comparing the cholesterol levels of a group of subjects who lose weight by dieting with a control group that does not diet. The difference between groups in cholesterol is not significant. Can the researcher claim that weight loss has no effect?