2. In a William Ether Synthesis of Phenacetin experiment, the organic layer is washed twice with 5% aq. NaOH. The purpose of this step was to remove any unreacted acetaminophen from the organic layer by extracting it into the aqueous layer. a) What reaction is occurring between acetaminophen and NaOH? Draw the reaction, mechanism, and product of this reaction step.

Organic Chemistry: A Guided Inquiry
2nd Edition
ISBN:9780618974122
Author:Andrei Straumanis
Publisher:Andrei Straumanis
Chapter19: Eas: Electrophilic Aromatic Substitution
Section: Chapter Questions
Problem 6E
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b) Why is the product that you drew in part a) more soluble in the aqueous layer than
organic layer?
Transcribed Image Text:b) Why is the product that you drew in part a) more soluble in the aqueous layer than organic layer?
In a William Ether Synthesis of Phenacetin experiment, the organic layer is washed twice
with 5% aq. NaOH. The purpose of this step was to remove any unreacted acetaminophen from
the organic layer by extracting it into the aqueous layer.
2.
a) What reaction is occurring between acetaminophen and NaOH? Draw the
reaction,
mechanism, and product of this reaction step.
Transcribed Image Text:In a William Ether Synthesis of Phenacetin experiment, the organic layer is washed twice with 5% aq. NaOH. The purpose of this step was to remove any unreacted acetaminophen from the organic layer by extracting it into the aqueous layer. 2. a) What reaction is occurring between acetaminophen and NaOH? Draw the reaction, mechanism, and product of this reaction step.
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