4. An enzyme (acetoacetate decarboxylase) catalyzes the decarboxylation of acetoacetate. The mechanism has been studied extensively; concluding that the key bond-breaking step involves an enamine as a leaving group. Draw a curved arrow mechanism in the boxes below. Label the “iminium” and then “enamine" and then “iminium” as three consecutive intermediates in the mechanism. Note that the acid is stoichiometric PLUS catalytic. (Hint: acid-base involving oxygen should be drawn concerted with other steps) Enz 요요 (cat.) NH2 EnzAH EnzAH (cat.) O=C=0 EnzA

Refer to the reaction energy diagram to answer parts (a) through (e). (a) What is the rate-limiting STEP? (Select from 1, 2, 3, or 4) (b) The TRANSITION STATE for the fastest step is: (c) In the 3rd step which INTERMEDIATE structurally resembles the transition state according to the Hammon postulate? (d) Which STEP NUMBER is endergonic? (e) The number of intermediates in the overall reaction is:

Provide an arrow pushing mechanism for the following reaction. Include protons and each step clearly indicated. OEt NaOEt, EtOH EtO OEt OEt OEt NaOEt, EtOH then H* work up

On a scrap piece of paper, draw a curved arrow mechanism for the following reaction. Once you have determined the major organic product, draw it in the space provided below. -Br 1) Ph P 2) n-BuLi 3) H

1. Take a close look at the following reactions. (a) Draw the product in the box below. (b) Provide the mechanism in the space below the reaction scheme. H₂O, H₂SO4

Use a scrap piece of paper to draw the curved arrow mechanism for the reaction below. Use your mechanism to help you determine the major organic product formed, then draw it in the space provided.

help please answer in text form with proper workings and explanation for each and every part and steps with concept and introduction no AI no copy paste remember answer must be in proper format with all working

Synthesise the target molecules drawn below using precursor chemicals within the following limitations: 1) ALL intermediates and reagents must be shown.2) Each molecule requires multiple step synthesis.3) You must also synthesize any organometallic reagents or ligands that you wish to use. a) Aspirin is a common pain killer that was developed by Bayer.

On a scrap piece of paper, draw the curved arrow mechanism for the preferred reaction pathway of the following reaction. Assume an aqueous workup at the end of the reaction and draw the major organic products in the space provided. O O He NH₂ + Y N.

Bha Please don't provide the handwriting solution