2. A polypeptide for a gene has the following amino acid sequence: Met-Ser-Pro-Arg-Leu-Glu-Gly The mutant amino acid sequences below were derived from the same gene. For each mutant, indicate which codon contains the mutations, the type of mutation (single-base substitution - transition or tranversion, insertion, deletion) that occurred in the DNA, and the phenotypic effect of the mutation. For example, if it is a single-base substitution, does it result in a missense or nonsense mutation? If it is an insertion or deletion, is it in-frame or does it result in a frameshift? a. Mutant 1: Met-Ser-Ser-Arg-Leu-Glu-Gly b. Mutant 2: Met-Ser-Pro c. Mutant 3: Met-Ser-Pro-Asp-Trp-Arg-Asp-Lys d. Mutant 4: Met-Ser-Pro-Glu-Gly
2. A polypeptide for a gene has the following amino acid sequence: Met-Ser-Pro-Arg-Leu-Glu-Gly The mutant amino acid sequences below were derived from the same gene. For each mutant, indicate which codon contains the mutations, the type of mutation (single-base substitution - transition or tranversion, insertion, deletion) that occurred in the DNA, and the phenotypic effect of the mutation. For example, if it is a single-base substitution, does it result in a missense or nonsense mutation? If it is an insertion or deletion, is it in-frame or does it result in a frameshift? a. Mutant 1: Met-Ser-Ser-Arg-Leu-Glu-Gly b. Mutant 2: Met-Ser-Pro c. Mutant 3: Met-Ser-Pro-Asp-Trp-Arg-Asp-Lys d. Mutant 4: Met-Ser-Pro-Glu-Gly
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Gene Interactions
When the expression of a single trait is influenced by two or more different non-allelic genes, it is termed as genetic interaction. According to Mendel's law of inheritance, each gene functions in its own way and does not depend on the function of another gene, i.e., a single gene controls each of seven characteristics considered, but the complex contribution of many different genes determine many traits of an organism.
Gene Expression
Gene expression is a process by which the instructions present in deoxyribonucleic acid (DNA) are converted into useful molecules such as proteins, and functional messenger ribonucleic (mRNA) molecules in the case of non-protein-coding genes.
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Transcribed Image Text:2. A polypeptide for a gene has the following amino acid sequence:
Met-Ser-Pro-Arg-Leu-Glu-Gly
The mutant amino acid sequences below were derived from the same gene. For
each mutant, indicate which codon contains the mutations, the type of mutation
(single-base substitution - transition or tranversion, insertion, deletion) that
occurred in the DNA, and the phenotypic effect of the mutation. For example, if it
is a single-base substitution, does it result in a missense or nonsense mutation?
If it is an insertion or deletion, is it in-frame or does it result in a frameshift?
a. Mutant 1: Met-Ser-Ser-Arg-Leu-Glu-Gly
b. Mutant 2: Met-Ser-Pro
c. Mutant 3: Met-Ser-Pro-Asp-Trp-Arg-Asp-Lys
d. Mutant 4: Met-Ser-Pro-Glu-Gly
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