2) Attenuation of the trp operon is controlled by the formation of stem-loop structures in the mRNA of the trpl region. The attenuation function can be disrupted by mutations that alter the sequence of the repeat DNA regions 1-4 and prevent formation of the RNA stem loops. Describe the most likely effects on attenuation of each of the following mutation under the conditions specified. a. Mutation in region 1 and low levels of tryptophan: b. Mutation in region 2 and low levels of tryptophan: C. Mutation in region 2 and moderate levels of tryptophan (low enough to release the repression but enough to allow the ribosome to NOT pause):

Human Anatomy & Physiology (11th Edition)
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Author:Elaine N. Marieb, Katja N. Hoehn
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Chapter1: The Human Body: An Orientation
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2) Attenuation of the trp operon is controlled by the formation of stem-loop structures in the mRNA
of the trpl region. The attenuation function can be disrupted by mutations that alter the sequence
of the repeat DNA regions 1-4 and prevent formation of the RNA stem loops. Describe the most
likely effects on attenuation of each of the following mutation under the conditions specified.
a. Mutation in region 1 and low levels of tryptophan:
b. Mutation in region 2 and low levels of tryptophan:
Mutation in region 2 and moderate levels of tryptophan (low enough to release the
repression but enough to allow the ribosome to NOT pause):
с.
d. Mutation in region 3 and low levels of tryptophan:
е.
Mutation in region 3 and moderate levels of tryptophan (low enough to release the
repression but enough to allow the ribosome to NOT pause):
f.
Mutation in region 4 and low levels of tryptophan:
Transcribed Image Text:2) Attenuation of the trp operon is controlled by the formation of stem-loop structures in the mRNA of the trpl region. The attenuation function can be disrupted by mutations that alter the sequence of the repeat DNA regions 1-4 and prevent formation of the RNA stem loops. Describe the most likely effects on attenuation of each of the following mutation under the conditions specified. a. Mutation in region 1 and low levels of tryptophan: b. Mutation in region 2 and low levels of tryptophan: Mutation in region 2 and moderate levels of tryptophan (low enough to release the repression but enough to allow the ribosome to NOT pause): с. d. Mutation in region 3 and low levels of tryptophan: е. Mutation in region 3 and moderate levels of tryptophan (low enough to release the repression but enough to allow the ribosome to NOT pause): f. Mutation in region 4 and low levels of tryptophan:
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