Biochemistry
Biochemistry
9th Edition
ISBN: 9781319114671
Author: Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher: W. H. Freeman
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14. Since ancient times it has been observed that certain game birds, such as grouse, quail, and
pheasants, are easily fatigued. The Greek historian Xenophon wrote, "The bustards... can be
caught if one is quick in starting them up, for they will fly only a short distance, like partridges,
and soon tire; and their flesh is delicious." The flight muscles of game birds rely almost entirely
on the use of glucose 1-phosphate for energy, in the form of ATP. The glucose 1-phosphate is
formed by the breakdown of stored muscle glycogen, catalysed by the enzyme glycogen
phosphorylase. The rate of ATP production is limited by the rate at which glycogen can be
broken down. During a "panic flight," the game bird's rate of glycogen breakdown is quite
high, approximately 120 μmol/min of glucose 1-phosphate produced per gram of fresh tissue.
Given that the flight muscles usually contain about 0.35% glycogen by weight, calculate how
long a game bird like a 5-pound grouse can fly. (Assume the average molecular weight of a
glucose residue in glycogen is 162 g/mol. One pound is equal to. 0.454 kg.)
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Transcribed Image Text:14. Since ancient times it has been observed that certain game birds, such as grouse, quail, and pheasants, are easily fatigued. The Greek historian Xenophon wrote, "The bustards... can be caught if one is quick in starting them up, for they will fly only a short distance, like partridges, and soon tire; and their flesh is delicious." The flight muscles of game birds rely almost entirely on the use of glucose 1-phosphate for energy, in the form of ATP. The glucose 1-phosphate is formed by the breakdown of stored muscle glycogen, catalysed by the enzyme glycogen phosphorylase. The rate of ATP production is limited by the rate at which glycogen can be broken down. During a "panic flight," the game bird's rate of glycogen breakdown is quite high, approximately 120 μmol/min of glucose 1-phosphate produced per gram of fresh tissue. Given that the flight muscles usually contain about 0.35% glycogen by weight, calculate how long a game bird like a 5-pound grouse can fly. (Assume the average molecular weight of a glucose residue in glycogen is 162 g/mol. One pound is equal to. 0.454 kg.)
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