102. A 29-year-old woman who is an intravenous drug user is found to have increased serum AST and ALT activities. Immunologic testing shows positive results for hepatitis B surface antigenand total antibody to hepatitis B core antigen, and negative results for IgM antibody to hepatitis B core antigen. This patient will recover from this hepatitis B virus infection and be protectedfrom subsequent similar infections with this virus if she generates which of the following immune responses?A) Cytotoxic T-lymphocyte responseB) Production of neutralizing antibodiesC) Type II (complement-mediated cytotoxic) hypersensitivity responseD) Type III (immune complex-mediated) hypersensitivity responseE) Type IV (delayed) hypersensitivity response

Serum AST and ALT Activities: They are found primarily in liver cells. When liver cells are damaged,…

Answered: 102. A 29-year-old woman who is an…

Phlebotomy Essentials

6th Edition

ISBN:9781451194524

Author:Ruth McCall, Cathee M. Tankersley MT(ASCP)

Publisher:Ruth McCall, Cathee M. Tankersley MT(ASCP)

Chapter1: Phlebotomy: Past And Present And The Healthcare Setting

Section: Chapter Questions

Problem 1SRQ

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Compare and contrast herd immunity from vaccination between pneumococcal pneumonia and COVID-19.
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Match the following term with its description or definition. Immunoglobulin domain Amino acids that are separated in the protein chain but come together in the folded protein Antigen that carries several epitopes of the same or different specificity Heavy chain classes Soluble proteins that carry only one copy of the epitope ✓ Choose... IgG, IgM, IgD, IgA, IgE Multivalent antigen Discontinuous epitope Monovalent antigen Repeated barrel-shaped structure Choose...
1) SDS PAGE gels can be probed with NBT/BCIP to perform an immunoblot true/ false 2) the direction of migration of protiens through a matrix is due to most proteins in natur having a net negative charge true/false 3) PBST is a buffer that is used for blocking the membrane during immunoblotting. true/false 4) the buffer used during for transferring proteins to nitrocellulose methanol. true/false 7) The size of the pores of a polyacrylamide gel dcreases as concentrations of polyacrylamide increases. True or false 10) The secondary antibody used in laboratory for western blotting is conjugated to which enzyme A) Alkaline decarboxylase B) GAPDH C) Alkaline Phosphatase D) Horseeradish peroxide 13) In protien electrophroresis, what reagent present in the sample buffer is used to eliminate difference in the charge densities of protein A) SDS B) 2- mercaptoethanol C) Tris-HCL pH6.8 D) Tris- HCL PH 8.8
10. Following a rattiesnake bite, a patient is injected with horse anti-rattlesnake venom serum. Ten days later, he has general weakness, headaches, muscular and joint pains, and dark urine. Laboratory studies show proteinuria. Serum concentrations of immunoglobulins are within the reference range, but serum C3 and C4 concentrations are decreased. Which of the following is the most likely pathologic process? A) Anaphylactic reaction ( Dj Delayed hypersensitivity to horse proteins (✔ Formation of antigen-antibody complexes containing horse proteins and/human immunoglobulins Formation of antigen-antibody complexes containing snake venom proteins and horse antibody Systemic reaction to snake venom Senum Sichness туре !!! Суренийнis (CL
142. A 1-year-old boy has had recurrent pyogenic infections of the skin and upper respiratory tract. His brother died at the age of 6 months from an undiagnosed infection; his sister appears healthy. Laboratory studies of serum show: IgG IgA, IgM Peripheral lymphocytes 120 mg/dL undetectable 80% T lymphocytes, <1% B lymphocytes Which of the following findings is most likely on examination of tonsillar tissue? OA) Absence of lymphoid follicles and germinal centers B) Absence of macrophages C) Decreased cellularity of the parafollicular cortex D) Hyperplasia of endothelial cells lining lymphatic sinusoids E) Increased numbers of eosinophils and plasma cells
(i) Serum sickness belongs to what type of hypersensitivity? What causes serum sickness? (ii) Serum sickness does begin immediately upon the production of anti-BSA antibodies. How does the amount of antibody present relate to the formation of large or small immune complexes? Explain which of these would trigger serum sickness?
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(26) A laboratory animal is shceduled to be immunized by receiving 3 weekly injections of antigen X. After the last immunization, it is discovered that the preparation used for the final immunizaton was not purified to homogeinity and also contained antigen Y. Which of the following is the most likely to be the primary class of the antibodies to antigen Y in the blood drawn 2 days after the klast injection (A) IgA (B) IgD (C) IgE (D) IgG (E) IgM

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