Chemistry
Chemistry
10th Edition
ISBN: 9781305957404
Author: Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher: Cengage Learning
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**Synthesis Process and Mechanism Overview**

This educational material outlines a multi-step organic synthesis process represented by a sequence of chemical reactions. Each step involves specific reagents and leads to the formation of intermediates and a final product. The text explains the synthetic pathway involving the conversion of an initial compound through intermediates to the final product.

**Process Steps:**

1. **Provide the structure of Intermediate A.**
2. **Provide a mechanism for the formation of Intermediate A.**
3. **Provide the structure of Intermediate B.**
4. **Provide a mechanism for the formation of Intermediate B.**
5. **Provide a mechanism for the formation of the final product.**

**Chemical Reaction Pathway:**

- Starting Compound: An aromatic aldehyde with methoxy and hydroxyl groups.
- **Step 1:** Reaction with a methyl-substituted aniline forms Imine Intermediate A (not isolated).
- **Step 2:** Reduction by sodium borohydride (NaBH₄) in ethanol (EtOH) creates Amine Intermediate B (not isolated).
- **Step 3:** Acetylation with acetic anhydride (Ac₂O) forms the final product, which is an acetylated amine.

**Diagram Explanation:**

- The initial arrow labeled “1” indicates the reaction between the aldehyde and aniline to form the imine.
- The subsequent step noted as “2” shows the reduction process leading to the formation of an amine.
- The arrow labeled “3” represents acetylation, indicating the final transformation into the acetylated amine with a lactam ring structure.

This sequence describes a typical process for synthesizing a complex organic molecule via a planned strategy of reactions and transformations.
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Transcribed Image Text:**Synthesis Process and Mechanism Overview** This educational material outlines a multi-step organic synthesis process represented by a sequence of chemical reactions. Each step involves specific reagents and leads to the formation of intermediates and a final product. The text explains the synthetic pathway involving the conversion of an initial compound through intermediates to the final product. **Process Steps:** 1. **Provide the structure of Intermediate A.** 2. **Provide a mechanism for the formation of Intermediate A.** 3. **Provide the structure of Intermediate B.** 4. **Provide a mechanism for the formation of Intermediate B.** 5. **Provide a mechanism for the formation of the final product.** **Chemical Reaction Pathway:** - Starting Compound: An aromatic aldehyde with methoxy and hydroxyl groups. - **Step 1:** Reaction with a methyl-substituted aniline forms Imine Intermediate A (not isolated). - **Step 2:** Reduction by sodium borohydride (NaBH₄) in ethanol (EtOH) creates Amine Intermediate B (not isolated). - **Step 3:** Acetylation with acetic anhydride (Ac₂O) forms the final product, which is an acetylated amine. **Diagram Explanation:** - The initial arrow labeled “1” indicates the reaction between the aldehyde and aniline to form the imine. - The subsequent step noted as “2” shows the reduction process leading to the formation of an amine. - The arrow labeled “3” represents acetylation, indicating the final transformation into the acetylated amine with a lactam ring structure. This sequence describes a typical process for synthesizing a complex organic molecule via a planned strategy of reactions and transformations.
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