1. Methylation of DNA and acetylation of histones are directly correlated. 2. Histone demethylation and acetylation are both for gene inactivation. OA.Only the first statement is true. OB.Only the second statement is true. OC. Both statements are true. OD. Both statements are false.

2. A researcher attempts to repeat the experiment in which genetic engineering was used to transform cells in culture with the Xist gene. When the Xist gene was targeted to chromosome 21 in cells from a person with Down syndrome (trisomy 21), transcription of the copy of chromosome 21 containing Xist was shut down, much like the inactive X chromosome in cells from a normal female. After carrying out the experiment, the researcher measures the level of transcription averaged over a sample of genes in chromosome 21 and, as a control, measures the level of transcription of a sample of genes in chromosome 6. Shown here are several possible outcomes of such an experiment. Type of cell line Normal | 47,+21 1 47,+21 and Xist transformed 2.0 M 1.5 H K L 1.0 0.5 Chsm 6 Chsm 21 Chsm 6 Chsm 21 Chsm 6 Chsm 21 Chsm 6 Chsm 21 Chsm 6 Chsm 21 Biology: How Life Works, Third Edition O 2019 Macmillan Learning Which bar graph suggests that the experiment succeeded (that is, that the Xist gene became…

Mutations that occur in enhancer sequences would most likely affect the cell by ____.   altering the translational process of the RNA that is made from that gene.   altering the functional ability of the protein that is made   reducing the amount of RNA made that is encoded in that gene   reducing the amount of protein made

20. Genome imprinting can be the result of silencing genes by methylation of promoter DNA sequences. Which of the following is true? A. They directly inhibit RNA transcription. B. They directly inhibit protein translation. C. They directly inhibit nuclear pore transport. D. They directly inhibit ribosome assembly E. They reduce protein stability.