1. It is observed that as temperature is increased, most protein molecules go from their defined, folded state into a random-coil, denatured state that exposes more hydrophobic surface area than is exposed in the folded state. (a) Given what you have learned so far about AH and AS, explain why this is reasonable. (b) Sometimes, however, proteins denature as temperature is decreased. How might this be explained?

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1. It is observed that as temperature is increased, most protein molecules go
from their defined, folded state into a random-coil, denatured state that
exposes more hydrophobic surface area than is exposed in the folded state.
(a) Given what you have learned so far about AH and AS, explain why this
is reasonable.
(b) Sometimes, however, proteins denature as temperature is decreased. How
might this be explained?
Transcribed Image Text:1. It is observed that as temperature is increased, most protein molecules go from their defined, folded state into a random-coil, denatured state that exposes more hydrophobic surface area than is exposed in the folded state. (a) Given what you have learned so far about AH and AS, explain why this is reasonable. (b) Sometimes, however, proteins denature as temperature is decreased. How might this be explained?
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