1. Determine the Michaelis-Menten parameters of Vmax and K for the reaction S+E E.S₂E+S E.S E.S+W P+E The rate of reaction is given as a function of substrate: [S] 0.2 0.02 0.01 kmol/m³ -I'S kmol/m³.s 0.54 0.28 0.19 0.005 0.1 0.002 0.045

The experiment is about testing the ideal gas law (magnesium ribbon experiment)

Your current Vmax (4x10-3 A/S) from the Michaelis-Menten plot has the units of  A/s and was determined using 0.1 mg of ADH in a total volume of 1.25 mL. Use the Beer-Lambert equation followed by simple conversion to express your estimated Vmax in (mol )/s per 1 mg ADH. The molar absorptivity of NADH at 340 nm is 6220 L/(mol*cm).

A doctor wants to prescribe a 70 kg patient a drug to be taken PO. In order to achieve an average steady-state plasma concentration (Css) of this drug in its therapeutic range, the patient needs to have a of Css of 597 μg/L. The VD of this drug is 2.3 L/kg, the F of this drug is 0.70, and the half-life of this drug is 12.9 hours. What is the necessary dosing regimen needed to achieve the desired Css? (units: mg/day, i.e., mg/24 h))